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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국약제학회 Journal of Pharmaceutical Investigation Journal of Pharmaceutical Investigation 제49권 제3호
- 발행연도
- 2019.1
- 수록면
- 287 - 294 (8page)
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Adipose tissue-derived mesenchymal stem cells (ADSCs) can be expanded in vitro and differentiated into numerous specialized cell types because of their self-renewal and multipotential differentiation properties. Their main advantage over other tissue-derived mesenchymal stem cells is in being easily and repeatedly harvested using minimally invasive techniques with low morbidity. They have been used for tissue repair and regeneration and are currently recognized as attractive candidates for substituting tissue or organ transplantation. Ion channels and transporters are involved in various cell responses, which make them fascinating drug targets. This logic may also be applicable to ADSC and therefore, it is necessary to arrange ADSC’s ion channels and transporters information. Ion channels and transporters are involved in dynamic changes in survival, proliferation, and differentiation of ADSCs. Their protein expressions are heterogeneous among different types of stem cells. They are involved in regulating excitation genesis and impulse conduction in excitable cells and they play a role in cell proliferation, migration, and apoptosis in proliferative cells. This review aims to provide a brief overview of the expression of various ion channels and transporters in ADSCs and to discuss their functional roles in the proliferation and differentiation of ADSCs.
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참고문헌 (67)
참고문헌 신청
Abbott BL / 2006 / ABCG2(BCRP) : a cytoprotectant in normal and malignant stem cells / Clin Adv Hematol Oncol 4(1):63~72
Abrahamse H / 2017 / Photomedicine and stem cells: the Janus face of photodynamic therapy (PDT) to kill cancer stem cells, and photobiomodulation (PBM) to stimulate normal stem cells / IOP Concise Physics :135
Acosta E / 2011 / Na+ (2011)K+-ATPase genes are down-regulated during adipose stem cell differentiation / Front Biosci (Elite Ed) 3:1229~1240
Ang VT / 1984 / Neurohypophysial hormones in the adrenal medulla / J Clin Endocrinol Metab 58(4):688~691
Beech DJ / 2004 / Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP / J Physiol 559(Pt 3):685~706
Abrahamse H / 2017 / Photomedicine and stem cells: the Janus face of photodynamic therapy (PDT) to kill cancer stem cells, and photobiomodulation (PBM) to stimulate normal stem cells / IOP Concise Physics :135
Acosta E / 2011 / Na+ (2011)K+-ATPase genes are down-regulated during adipose stem cell differentiation / Front Biosci (Elite Ed) 3:1229~1240
Ang VT / 1984 / Neurohypophysial hormones in the adrenal medulla / J Clin Endocrinol Metab 58(4):688~691
Beech DJ / 2004 / Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP / J Physiol 559(Pt 3):685~706
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