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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.12
- 수록면
- 313 - 320 (8page)
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In this study, phytochemicals extracted from sea mustard (SM) and sea mustard sporophyll (SMS) in ethanol solution have been analyzed and wound healing potential of the phytochemicals was investigated. In the phytochemical screening studies, the extract of SM and SMS includes several phytochemical compounds such as phytol, ascorbic acid, sitgmasta, fucosterol and ergosta. Cytotoxicity studies of the extract of SM and SMS with mouse macrophage RAW 264.7 cells showed on toxicity up to a high concentration of 1.0 mg/mL. Furthermore, the SM and SMS extract significantly reduces the production of nitric oxide (NO) induced lipopolysaccharide on RAW 264.7 cells with a dose-dependent manner. In addition, the extract of SM and SMS has the effect of enhancing the cell migration and invasion of fibroblast. These results demonstrate that the extract of SM and SMS could help to heal wound by reducing NO production and increasing cell migration
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REFERENCES
참고문헌 (28)
참고문헌 신청
안선미 / 2010 / 35종 해조류 추출물의 in-vitro 항혈전 활성 평가 / 생명과학회지 20(11):1640~1647
Alfadda AA / 2012 / Reactive oxygen species in health and disease / Journal of Biomedicine and Biotechnology :936486
Blois MS / 1958 / Antioxidant determinations by the use of a stable free radical / Nature 181:1199~1200
Burčová Z / 2018 / Antibacterial and antifungal activity of phytosterols and methyl dehydroabietate of Norway spruce bark extracts / Journal of Biotechnology 20:18~24
Chung JH / 1997 / Regulations of collagen synthesis by ascorbic acid, transforming growth factor‐beta and interferon‐gamma in human dermal fibroblasts cultured in three‐dimensional collagen gel are photoaging and aging independent / Journal of Dermatological Science 15:188~200
Alfadda AA / 2012 / Reactive oxygen species in health and disease / Journal of Biomedicine and Biotechnology :936486
Blois MS / 1958 / Antioxidant determinations by the use of a stable free radical / Nature 181:1199~1200
Burčová Z / 2018 / Antibacterial and antifungal activity of phytosterols and methyl dehydroabietate of Norway spruce bark extracts / Journal of Biotechnology 20:18~24
Chung JH / 1997 / Regulations of collagen synthesis by ascorbic acid, transforming growth factor‐beta and interferon‐gamma in human dermal fibroblasts cultured in three‐dimensional collagen gel are photoaging and aging independent / Journal of Dermatological Science 15:188~200
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UCI(KEPA) : I410-ECN-0101-2020-510-000238618