지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충북대학교 동물의학연구소 Journal of Biomedical and Translational Research Journal of Biomedical and Translational Research 제20권 제4호
- 발행연도
- 2019.1
- 수록면
- 99 - 104 (6page)
이용수
초록· 키워드
오류제보하기
The interaction between the cardiac and renal systems is important in determining blood pressure and blood volume, both of which play a role in the vasomotor system and fluid balance. Cardiorenal syndrome (CRS) occurs as a result of a disparity in correlation between the two. In veterinary medicine, cardiovascular-renal axis disorder (CvRD) lacks pathologically and etiologically specific data, but shares common pathophysiological patterns with CRS and CvRD in humans. CvRD is structural or functional damage caused by diseases of the heart or kidneys, or toxins or drugs, resulting in the disruption of normal interactions between these organs and the destruction of one or both organs. The aim of this study is to compare the long-term changes in various indicators, including hypertension, proteinuria and echocardiographic parameters, before and after administration of telmisartan in cats with CvRD. This study found a clear gradual decrease in Urine protein to creatinine (UP/C) ratio and left atrium (LA) diameter in cats with CvRD, after administration of telmisartan. UP/C ratio (p<0.001) was found to decrease significantly over time, after administration of telmisartan. UP/C ratio before telmisartan administration was 0.39 ± 0.255 (Day 0) and 0.29 ± 0.056 on day 30 (Day 30), 0.28 ± 0.040 on day 60 (Day 60), and 0.20 ± 0.128 on day 90 (Day 90) after administration, respectively. LA diameter before telmisartan administration was 17.9 mm ± 1.6 before telmisartan administration (Day 0) and 17.4 mm ± 1.8 on day 30 (Day 30), 16.1 mm ± 1.6 on day 60 (Day 60), and 15.7 mm ± 1.7 on day 90 (Day 90) after administration, respectively. Oral administration of telmisartan to cats with CvRD is effective in improving proteinuria and LA diameter, which is a positive aspect of long-term survival in cats with CvRD.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Ronco C / 2008 / Cardiorenal syndrome / J Am Coll Cardiol 52:1527~1539
Orvalho JS / 2017 / Cardiorenal syndrome : diagnosis and management / Vet Clin North Am Small Anim Pract 47:1083~1102
Pouchelon JL / 2015 / Cardiovascular-renal axis disorders in the domestic dog and cat : a veterinary consensus statement / J Small Anim Pract 56:537~552
Nicolle AP / 2007 / Azotemia and glomerular filtration rate in dogs with chronic valvular disease / J Vet Intern Med 21:943~949
Chetboul V / 2012 / Renal resistive index in 55 dogs with degenerative mitral valve disease / J Vet Intern Med 26:101~108
Orvalho JS / 2017 / Cardiorenal syndrome : diagnosis and management / Vet Clin North Am Small Anim Pract 47:1083~1102
Pouchelon JL / 2015 / Cardiovascular-renal axis disorders in the domestic dog and cat : a veterinary consensus statement / J Small Anim Pract 56:537~552
Nicolle AP / 2007 / Azotemia and glomerular filtration rate in dogs with chronic valvular disease / J Vet Intern Med 21:943~949
Chetboul V / 2012 / Renal resistive index in 55 dogs with degenerative mitral valve disease / J Vet Intern Med 26:101~108
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