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- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 1 - 17 (17page)
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Coronavirus disease 2019 (COVID-19), which started at the end of 2019 and has spread worldwide, has remained unabated in 2021. Since non-pharmaceutical interventions including social distancing are facing limitations in controlling COVID-19, additional absolute means to change the trend are necessary. To this end, coronavirus-specific antiviral drugs and vaccines are urgently needed, but for now, the priority is to promote herd immunity through extensive nationwide vaccination campaign. In addition to the vaccines based on the conventional technology such inactivated or killed virus or protein subunit vaccines, several vaccines on the new technological platforms, for example, nucleic acids-based vaccines delivered by viral carriers, nanoparticles, or plasmids as a medium were introduced in this pandemic. In addition to achieving sufficient herd immunity with vaccination, the development of antiviral treatments that work specifically against COVID-19 will also be necessary to terminate the epidemic completely.
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참고문헌 (69)
참고문헌 신청
Schlake T / 2012 / Developing mRNA-vaccine technologies / RNA Biol 9(11):1319~1330
Anderson BR / 2011 / Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L / Nucleic Acids Res 39(21):9329~9338
Zhang Z / 2016 / Structural analysis reveals that Toll-like receptor 7 is a dual receptor for guanosine and single-stranded RNA / Immunity 45(4):737~748
Karikó K / 2005 / Suppression of RNA recognition by Toll-like receptors : the impact of nucleoside modification and the evolutionary origin of RNA / Immunity 23(2):165~175
Tanji H / 2015 / Toll-like receptor 8 senses degradation products of single-stranded RNA / Nat Struct Mol Biol 22(2):109~115
Anderson BR / 2011 / Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L / Nucleic Acids Res 39(21):9329~9338
Zhang Z / 2016 / Structural analysis reveals that Toll-like receptor 7 is a dual receptor for guanosine and single-stranded RNA / Immunity 45(4):737~748
Karikó K / 2005 / Suppression of RNA recognition by Toll-like receptors : the impact of nucleoside modification and the evolutionary origin of RNA / Immunity 23(2):165~175
Tanji H / 2015 / Toll-like receptor 8 senses degradation products of single-stranded RNA / Nat Struct Mol Biol 22(2):109~115
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