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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.2
- 수록면
- 44 - 61 (18page)
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초록· 키워드
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The global outbreak of coronavirus disease 2019 (COVID-19) is still threatening human health, economy, and social life worldwide. As a counteraction for this devastating disease, a number of vaccines are being developed with unprecedented speed combined with new technologies. As COVID-19 vaccines are being developed in the absence of a licensed human coronavirus vaccine, there remain further questions regarding the long-term efficacy and safety of the vaccines, as well as immunological mechanisms in depth. This review article discusses the current status of COVID-19 vaccine development, mainly focusing on antigen design, clinical trials in later stages, and immunological considerations for further study.
목차
ABSTRACT
INTRODUCTION
SEVERE ACUTE RESPIRATORY SYNDROMECORONAVIRUS 2 (SARS-CoV-2)
SPIKE: A MAJOR TARGET ANTIGEN FOR COVID-19VACCINES
COVID-19 VACCINES IN LATER STAGES OF DEVELOPMENT
EFFICACY AND SAFETY OF COVID-19 VACCINES
CONCLUDING REMARKS
REFERENCES
참고문헌 (96)
참고문헌 신청
World Health Organization / Draft landscape of COVID-19 candidate vaccines
이푸름 / 2020 / Newly Emerging Human Coronaviruses: Animal Models and Vaccine Research for SARS, MERS, and COVID-19 / Immune Network 20(4):1~25
Gu H / 2020 / Adaptation of SARSCoV-2 in BALB/c mice for testing vaccine efficacy / Science 369:1603~1607
Wrapp D / 2020 / Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation / Science 367:1260~1263
Hamming I / 2004 / Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis / J Pathol 203:631~637
이푸름 / 2020 / Newly Emerging Human Coronaviruses: Animal Models and Vaccine Research for SARS, MERS, and COVID-19 / Immune Network 20(4):1~25
Gu H / 2020 / Adaptation of SARSCoV-2 in BALB/c mice for testing vaccine efficacy / Science 369:1603~1607
Wrapp D / 2020 / Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation / Science 367:1260~1263
Hamming I / 2004 / Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis / J Pathol 203:631~637
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