지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 688 - 696 (9page)
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초록· 키워드
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Background: Only a few studies have established the epidemiology of prolactinoma and Cushing’s disease in Korea. Furthermore, the incidence of these disease are increasing than before associated with the development of technologies. This study was designed to evaluate the epidemiology of prolactinoma and Cushing’s disease and their survival analysis according to treatment. Methods: The nationwide, population-based study evaluated incidence and prevalence of prolactinoma and Cushing’s disease using de-identified claims data in The Korean Health Insurance Review and Assessment Service database between 2013 and 2017. The survival analysis investigated regarding treatment over a period of 6 years. A log-rank test and Cox proportional hazard regression analysis were used. Results: The 6,056 patients with newly diagnosed prolactinoma and 584 patients with Cushing’s disease were recorded between 2013 and 2017. The annual incidence of prolactinoma was 23.5 cases per million, and its prevalence was 82.5 cases per million, and 2.3 cases per million/year and 9.8 cases per million for Cushing’s disease. The survival benefit was insignificant in prolactinoma according to treatment, but the treatment of Cushing’s disease improved the survival rate significantly. Conclusion: Overall, the incidence of prolactinoma and Cushing’s disease was similar with those found previously, but the prevalence of two diseases were inconsistent when compared with the early studies. The present study also proposed necessity of treatment in Cushing’s disease for improving the survival rate.
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참고문헌 (32)
참고문헌 신청
Daly AF / 2006 / High prevalence of pituitary adenomas : a cross-sectional study in the province of Liege, Belgium / J Clin Endocrinol Metab 91:4769~4775
Etxabe J / 1994 / Morbidity and mortality in Cushing’s disease: an epidemiological approach / Clin Endocrinol(Oxf) 40:479~484
Nilsson B / 2000 / Pituitary adenomas in Sweden between 1958 and 1991 : incidence, survival, and mortality / J Clin Endocrinol Metab 85:1420~1425
Park KH / 2015 / Rare intractable pituitary diseases: analysis on their epidemiology and use of benefit extension policy
Day PF / 2016 / Incidence and prevalence of clinically relevant pituitary adenomas : retrospective cohort study in a Health Management Organization in Buenos Aires, Argentina / Arch Endocrinol Metab 60:554~561
Etxabe J / 1994 / Morbidity and mortality in Cushing’s disease: an epidemiological approach / Clin Endocrinol(Oxf) 40:479~484
Nilsson B / 2000 / Pituitary adenomas in Sweden between 1958 and 1991 : incidence, survival, and mortality / J Clin Endocrinol Metab 85:1420~1425
Park KH / 2015 / Rare intractable pituitary diseases: analysis on their epidemiology and use of benefit extension policy
Day PF / 2016 / Incidence and prevalence of clinically relevant pituitary adenomas : retrospective cohort study in a Health Management Organization in Buenos Aires, Argentina / Arch Endocrinol Metab 60:554~561
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