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논문 기본 정보

자료유형
학술저널
저자정보
Akiko Kuwabara (Department of Health and Nutrition Osaka Shoin Wo) Naoko Tsugawa (Department of Hygienic Sciences Kobe Ph) Hiroshi Kondo (Gifu University Hospital) Misora Ao (Department of Food and Nutrition Kyoto Women's Un) Hitomi Fujiwara (Department of Health and Nutrition Osaka Shoin Wo) Natsuki Hosokawa (Osaka Shoin Women's University) Shiho Matsumoto (Osaka Shoin Women's University) Kiyoshi Tanaka (Kyoto Women's University) Tetsuo Nakano (Tamana Central Hospital)
저널정보
대한골다공증학회 Osteoporosis and Sarcopenia Osteoporosis and Sarcopenia Vol.3 No.1
발행연도
2017.1
수록면
53 - 58 (6page)

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Objectives: One of the important risk factors of falling is decreased muscle mass and muscle strength. Recently, there has been an increasing concern on the role of vitamin D in muscle strength and physical activity. Aim of our study is to examine the relationships between vitamin D status and muscle mass and muscle strength in middle-aged healthy adults. Methods: Subjects were 40 healthy volunteers aged 42.0 ± 10.6 years old. Evaluation was made for serum vitamin D3 metabolites including 25- hydroxyvitamin D3 [25(OH)D3] and 24,25-dihydroxyvitamin D3 [24,25(OH)2D3] concentrations, lower limb muscle strength, and dietary intake by food frequency questionnaire. Body composition was measured by dual-energy X-ray absorptiometry (DXA), and appendicular skeletal mass index (ASMI) was calculated as skeletal muscle mass/squared height. Results: 70% of the subjects had vitamin D insufficiency/deficiency (serum total 25(OH)D < 20 ng/mL), and female subjects had significantly lower serum total 25(OH)D level compared with males. Vitamin D insufficiency/deficiency group had significantly higher body fat, lower SMI and muscle strength, probably reflecting higher percentage of female subjects. Serum vitamin D3 metabolites levels were significantly correlated with whole and site-specific ASMI, and lower limb muscle strength, except for the correlation between serum 24,25(OH)2D3 concentration and lower limb muscle strength. In addition, serum 25(OH)D3 level was a positive significant predictor for both ASMI and lower limb muscle strength, while serum 24,25(OH)2D3 level was not their significant predictor. Conclusions: Serum 25(OH)D3 level was significantly correlated with both skeletal muscle mass and lower limb muscle strength.

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참고문헌 (27)

참고문헌 신청
Kalyani RR / 2010 / Vitamin D treatment for the prevention of falls in older adults: systematic review and meta-analysis / J Am Geriatr Soc 58:1299~1310 google schola Shimizu Y / 2015 / Serum 25-hydroxyvitamin D level and risk of falls in Japanese communitydwelling elderly women: a 1-year follow-up study / Osteoporos Int 26:2185~2192 google schola Sirola J / 2005 / Muscle performance after the menopause / J Br Menopause Soc 11:45~50 google schola Bischoff-Ferrari HA / 2009 / Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials / BMJ 339:b3692 google schola Halfon M / 2015 / A review on its effects on muscle strength, the risk of fall, and frailty / Biomed Res Int 2015:953241 google schola

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