지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한응급의학회 Clinical and Experimental Emergency Medicine Clinical and Experimental Emergency Medicine Vol.4 No.4
- 발행연도
- 2017.1
- 수록면
- 232 - 237 (6page)
이용수
초록· 키워드
오류제보하기
Objective To investigate whether serum levels of high-density lipoprotein (HDL) and apolipoprotein A-1 (ApoA1), after the return of spontaneous circulation, can predict the neurologic outcome in patients with out-of-hospital cardiac arrest (OHCA). Methods This was a retrospective observational study conducted in a single tertiary hospital intensive care unit. All adult OHCA survivors with admission lipid profiles were enrolled from March 2013 to December 2015. Good neurologic outcome was defined as discharge cerebral performance categories 1 and 2. Results Among 59 patients enrolled, 13 (22.0%) had a good neurologic outcome. Serum levels of HDL (56.7 vs. 40 mg/dL) and ApoA1 (117 vs. 91.6 mg/dL) were significantly higher in patients with a good outcome. Areas under the HDL and ApoA1 receiver operating curves to predict good outcomes were 0.799 and 0.759, respectively. The proportion of good outcome was significantly higher in patients in higher tertiles of HDL and ApoA1 (test for trend, both P=0.003). HDL (P=0.018) was an independent predictor in the multivariate logistic regression model. Conclusion Admission levels of HDL and ApoA1 are associated with neurologic outcome in patients with OHCA. Prognostic and potential therapeutic values of HDL and ApoA1 merit further evaluation in the post-cardiac arrest state, as in other systemic inflammatory conditions such as sepsis.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Centers for Disease Control and Prevention / CARES summary report: demographic and survival characteristics of OHCA
Shin SD / 2011 / Cardiopulmonary resuscitation outcome of out-of-hospital cardiac arrest in low-volume versus high-volume emergency departments: an observational study and propensity score matching analysis / Resuscitation 82:32~39
Roberts BW / 2013 / Multiple organ dysfunction after return of spontaneous circulation in postcardiac arrest syndrome / Crit Care Med 41:1492~1501
Adrie C / 2002 / Successful cardiopulmonary resuscitation after cardiac arrest as a “sepsis-like”syndrome / Circulation 106:562~568
Ingelsson E / 2007 / Clinical utility of different lipid measures for prediction of coronary heart disease in men and women / JAMA 298:776~785
Shin SD / 2011 / Cardiopulmonary resuscitation outcome of out-of-hospital cardiac arrest in low-volume versus high-volume emergency departments: an observational study and propensity score matching analysis / Resuscitation 82:32~39
Roberts BW / 2013 / Multiple organ dysfunction after return of spontaneous circulation in postcardiac arrest syndrome / Crit Care Med 41:1492~1501
Adrie C / 2002 / Successful cardiopulmonary resuscitation after cardiac arrest as a “sepsis-like”syndrome / Circulation 106:562~568
Ingelsson E / 2007 / Clinical utility of different lipid measures for prediction of coronary heart disease in men and women / JAMA 298:776~785
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
HDL Subclass Analysis in Predicting Metabolic Syndrome in Koreans With High HDL Cholesterol Levels
Annals of Laboratory Medicine
2020 .01
-
HDL-C and Cardiovascular Risk: You Don't Need to Worry about Extremely High HDL-C Levels
지질·동맥경화학회지
2021 .01
-
Higher High Density Lipoprotein 2 (HDL2) to Total HDL Cholesterol Ratio Is Associated with a Lower Risk for Incident Hypertension
Diabetes and Metabolism Journal
2019 .01
-
Lack of Evidence of the Role of APOA5 3’UTR Polymorphisms in Iranian Children and Adolescents with Metabolic Syndrome
Diabetes and Metabolism Journal
2018 .01
-
Association of High-Density Lipoprotein Cholesterol Phenotypes with the Risk of Cardiovascular Diseases and Mortality: A Cohort Study in Korea
Endocrinology and Metabolism
2022 .04
-
일개 도시에서 발생한 병원 밖 성인 심정지 환자들에 대한 분석 및 시계열 변화에 대한 고찰
대한응급의학회지
2023 .04
-
Repeated Low High-Density Lipoprotein Cholesterol and the Risk of Thyroid Cancer: A Nationwide Population-Based Study in Korea
Endocrinology and Metabolism
2022 .04
-
Calibration of High-Density Lipoprotein Cholesterol Values From the Korea National Health and Nutrition Examination Survey Data, 2008 to 2015
Annals of Laboratory Medicine
2017 .01
-
Risk assessment of metabolic syndrome in adolescents using the triglyceride/high-density lipoprotein cholesterol ratio and the total cholesterol/high-density lipoprotein cholesterol ratio
Annals of Pediatirc Endocrinology & Metabolism
2019 .01
-
Associations of Serum Lipid Level with Gastric Cancer Risk, Pathology, and Prognosis
Cancer Research and Treatment
2021 .01
-
한국 성인에서의 허리둘레와 고밀도 지단백 콜레스테롤의 관계: 국민건강영양조사 2015년 자료에 근거하여
Korean Journal of Family Practice
2019 .01
-
Sex-Specific U-Shaped Relationships Between High-Density Lipoprotein Cholesterol Levels and 10-year Major Adverse Cardiovascular Events: A Nationwide Cohort Study of 5.7 Million South Koreans
Annals of Laboratory Medicine
2022 .07
-
Apolipoprotein A1 Inhibits TGF-β1-Induced Epithelial-to-Mesenchymal Transition of Alveolar Epithelial Cells
Tuberculosis and Respiratory Diseases
2016 .01
-
Apolipoproteins as Differentiating and Predictive Markers for Assessing Clinical Outcomes in Patients with Small Cell Lung Cancer
Yonsei Medical Journal
2016 .01
-
Brain computed tomography angiography in postcardiac arrest patients and neurologic outcome
Clinical and Experimental Emergency Medicine
2019 .01
-
Prognostic significance of respiratory quotient in patients undergoing extracorporeal cardiopulmonary resuscitation in Korea
Acute and Critical Care
2023 .05
-
Vasospasm-related Sudden Cardiac Death Has Outcomes Comparable with Coronary Stenosis in Out-of-Hospital Cardiac Arrest
Journal of Korean Medical Science
2020 .01
-
High-Density Lipoprotein Cholesterol and the Risk of Myocardial Infarction, Stroke, and Cause-Specific Mortality: a Nationwide Cohort Study in Korea
지질·동맥경화학회지
2021 .01
-
항암치료 받는 악성 뇌종양 환자의 재발여부에 따른 지질프로필 비율의 비교
기초간호자연과학회지
2017 .01
-
Novel Associations between Related Proteins and Cellular Effects of High-Density Lipoprotein
Korean Circulation Journal
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0