지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 89 - 93 (5page)
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초록· 키워드
오류제보하기
Objective: The purpose of this study was to investigate the impact of continuous renal replacement therapy (CRRT) on survival and relevant factors in patients who underwent CRRT after traumatic brain injury (TBI). Methods: We retrospectively reviewed the laboratory, clinical, and radiological data of 29 patients who underwent CRRT among 1,190 TBI patients treated at our institution between April 2011 and June 2015. There were 20 men and 9 women, and the mean age was 60.2 years. The mean initial Glasgow Coma Scale score was 9.2, and the mean injury severity score was 24. Kaplan-Meier method and Cox regression were used for analysis of survival and relevant factors. Results: The actuarial median survival time of the 29 patients was 163 days (range, 3-317). Among the above 29 patients, 22 died with a median survival time of 8 days (range, 3-55). The causes of death were TBI-related in 8, sepsis due to pneumonia or acute respiratory distress syndrome (ARDS) in 4, and multi-organ failure in 10. Among the various factors, urine quantity of more than 500 mL for 24-hours before receiving CRRT was a significant and favorable factor for survival in the multivariate analysis (p=0.026). Conclusion: According to our results, we suggest that early intervention with CRRT may be beneficial in the treatment of TBI patients with impending acute renal failure (ARF). To define the therapeutic advantages of early CRRT in the TBI patients with ARF, a well-designed and controlled study with more cases is required.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Abbott NJ / 2006 / Astrocyte-endothelial interactions at the blood-brain barrier / Nat Rev Neurosci 7:41~53
Beaumont A / 2000 / The permissive nature of blood brain barrier (BBB) opening in edema formation following traumatic brain injury / Acta Neurochir Suppl 76:125~129
Becker DP / 1977 / The outcome from severe head injury with early diagnosis and intensive management / J Neurosurg 47:491~502
Davenport A / 1999 / Is there a role for continuous renal replacement therapies in patients with liver and renal failure? / Kidney Int Suppl :S62~S66
Davenport A / 2001 / Renal replacement therapy in the patient with acute brain injury / Am J Kidney Dis 37:457~466
Beaumont A / 2000 / The permissive nature of blood brain barrier (BBB) opening in edema formation following traumatic brain injury / Acta Neurochir Suppl 76:125~129
Becker DP / 1977 / The outcome from severe head injury with early diagnosis and intensive management / J Neurosurg 47:491~502
Davenport A / 1999 / Is there a role for continuous renal replacement therapies in patients with liver and renal failure? / Kidney Int Suppl :S62~S66
Davenport A / 2001 / Renal replacement therapy in the patient with acute brain injury / Am J Kidney Dis 37:457~466
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