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논문 기본 정보

자료유형
학술저널
저자정보
An Jung Nam (Department of Internal Medicine Hallym University Sacred Heart Hospital Anyang Republic of Korea) Kim Sung Gyun (Hallym University Sacred Heart Hospital Anyang Republic of Korea) 송영림 (한림대학교)
저널정보
대한신장학회 Kidney Research and Clinical Practice Kidney Research and Clinical Practice Vol.40 No.4
발행연도
2021.12
수록면
566 - 577 (12page)
DOI
10.23876/j.krcp.21.043

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Acute kidney injury (AKI) is a common condition in critically ill patients, and may contribute to significant medical, social, and econom- ic consequences, including death. Although there have been advances in medical technology, including continuous renal replacement therapy (CRRT), the mortality rate of AKI is high, and there is no fundamental treatment that can reverse disease progression. The de- cision to implement CRRT is often subjective and based primarily on the clinician’s judgment without consistent and concrete guide- lines or protocols regarding when to initiate and discontinue CRRT and how to manage complications. Recently, several randomized controlled trials addressing the initiation of renal replacement therapy in critically ill patients with AKI have been completed, but clini- cal application of the findings is limited by the heterogeneity of the objectives and research designs. In this review, the advantages and disadvantages of CRRT initiation, clinical guideline recommendations, and the results of currently published clinical trials and meta-analyses are summarized to guide patient care and identify future research priorities.

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