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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 162 - 165 (4page)
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초록· 키워드
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Background: Immunoglobulin G4 (IgG4) related disease is an immune-mediated fibroinflammatory condition that can affect multiple organs. There are only few reports of pachymeningeal involvement by IgG4 related disease in Korea. Case Report: A 50-year-old woman was admitted due to generalized seizure and headache. Brain magnetic resonance imaging (MRI) showed nodular dural thickening and enhancement in the right frontal areas. A meningeal biopsy was performed. On pathology, chronic inflammation, fibrosis and plasma cell infiltration were revealed. Immunoglobulin G4 immunohistochemistry showed prominent IgG4+ plasma cell infiltrate. Serum IgG level was normal but IgG4 subclass level was significantly elevated. She was treated with intravenous dexamethasone followed by oral prednisolone. After 1 year of treatment, brain MRI showed marked decrease of dural thickening and enhancement. Conclusions: We report a case of IgG4 related pachymeningitis improved with corticosteroid. IgG4 related disease should be included in the differential diagnosis in patients with hypertrophic pachymeningitis.
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등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Kamisawa T / 2015 / IgG4-related disease / Lancet 385:1460~1471
Choi SH / 2010 / IgG4-related sclerosing pachymeningitis causing spinal cord compression / Neurology 75:1388~1390
Hyun JW / 2014 / Steroidresistant relapsing IgG4-related pachymeningitis treated with methotrexate / JAMA Neurol 71:222~225
Sung Heon Kim / 2014 / Paraplegia in a Patient With IgG4-Related Sclerosing Disease: A Case Report / Annals of Rehabilitation Medicine 38(6):856~860
Jeong-Hyun Hwang / 2014 / Immunoglobulin G4-Related Hypertrophic Pachymeningitis with Skull Involvement / Brain Tumor Research and Treatment 2(2):87~91
Choi SH / 2010 / IgG4-related sclerosing pachymeningitis causing spinal cord compression / Neurology 75:1388~1390
Hyun JW / 2014 / Steroidresistant relapsing IgG4-related pachymeningitis treated with methotrexate / JAMA Neurol 71:222~225
Sung Heon Kim / 2014 / Paraplegia in a Patient With IgG4-Related Sclerosing Disease: A Case Report / Annals of Rehabilitation Medicine 38(6):856~860
Jeong-Hyun Hwang / 2014 / Immunoglobulin G4-Related Hypertrophic Pachymeningitis with Skull Involvement / Brain Tumor Research and Treatment 2(2):87~91
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