지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.4
- 수록면
- 344 - 358 (15page)
- DOI
- https://doi.org/10.3803/EnM.2021.1374
이용수
초록· 키워드
오류제보하기
Background: Although recent studies comparing various dosages and intervals of vitamin D supplementation have been published,it is yet to be elucidated whether there is an appropriate dose or interval to provide benefit regarding fracture risk. We aimed to assessthe published evidence available to date regarding the putative beneficial effects of vitamin D supplements on fractures and falls according to various dosages and intervals.
Methods: We performed a meta-analysis of randomized controlled studies reporting associations between vitamin D supplementation and the risks of fractures and falls in PubMed, EMBASE, and Cochrane library. Studies with supplements of ergocalciferol orcalcitriol, those with a number of event ≤10, or those with a follow-up duration of less than 6 months were also excluded.
Results: Thirty-two studies were included in the final analysis. Vitamin D supplementation with daily dose of 800 to 1,000 mg wasassociated with lower risks of osteoporotic fracture and fall (pooled relative risk [RR], 0.87; 95% confidence interval [CI], 0.78 to0.97 and RR, 0.91; 95% CI, 0.85 to 0.98), while studies with <800 or >1,000 mg/day did not. Also, among intervals, daily administration of vitamin D was associated with the reduced risk of falls, while intermittent dose was not. Also, patients with vitamin D deficiency showed a significant risk reduction of falls after vitamin D supplementation.
Conclusion: Daily vitamin D dose of 800 to 1,000 IU was the most probable way to reduce the fracture and fall risk. Further studiesdesigned with various regimens and targeted vitamin D levels are required to elucidate the benefits of vitamin D supplements.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Korean Society for Bone and Mineral Research Task Force Report: Perspectives on Intermittent High-dose Vitamin D Supplementation
대한골대사학회지
2017 .08
-
Vitamin D Levels in Patients with Low-energy Hip Fractures
Hip and Pelvis
2020 .01
-
Efficacy of Vitamin C Supplements in Prevention of Cancer: A Meta-Analysis of Randomized Controlled Trials
Korean Journal of Family Medicine
2015 .01
-
비타민D의 보충요법
대한의사협회지
2017 .01
-
Should We Measure Vitamin D Level?
Acute and Critical Care
2016 .01
-
Mechanistic Effects of Vitamin D Supplementation on Metabolic Syndrome Components in Patients with or without Vitamin D Deficiency
Journal of Obesity & Metabolic Syndrome
2020 .01
-
Preoperative Vitamin D Deficiency is Associated with Postoperative Functional Recovery and Complications after Hip Fracture Surgery
대한골대사학회지
2021 .11
-
The effect of metformin on vitamin B12 level in pediatric patients
Annals of Pediatirc Endocrinology & Metabolism
2022 .09
-
Effect of Vitamin D on the Treatment of Atopic Dermatitis With Consideration of Heterogeneities: Meta-Analysis of Randomized Controlled Trials
Allergy, Asthma & Immunology Research
2023 .03
-
Practical Vitamin D Supplementation Using Machine Learning
대한골대사학회지
2020 .01
-
Vitamin D in COVID - 19: Dousing the fire or averting the storm? e A perspective from the Asia-Pacific
Osteoporosis and Sarcopenia
2020 .01
-
Vitamin D and Hypertension
Electrolytes & Blood Pressure
2017 .01
-
The Effect of Education and Vitamin D Supplementation on the Achievement of Optimal Vitamin D Level in Korean Postmenopausal Women
대한골대사학회지
2019 .01
-
Vitamin-Mineral Supplement Use Patterns in Elderly Koreans: Data from the 2007–2008 Korean National Health and Nutrition Examination Survey
Korean Journal of Family Medicine
2016 .01
-
Position Statement: Vitamin D Intake to Prevent Osteoporosis and Fracture in Adults
대한골대사학회지
2022 .11
-
Cardiovascular Impact of Calcium and Vitamin D Supplements: A Narrative Review
Endocrinology and Metabolism
2023 .02
-
Vitamin D Deficiency Is Highly Concomitant but Not Strong Risk Factor for Mortality in Patients Aged 50 Year and Older with Hip Fracture
대한골대사학회지
2015 .01
-
Exploring optimal supplementation for people with vitamin D deficiency
Osteoporosis and Sarcopenia
2023 .03
-
Vitamin C Deficiency of Korean Homeless Patients Visiting to Emergency Department with Acute Alcohol Intoxication
Journal of Korean Medical Science
2015 .01
-
Vitamin D insufficiency and its contributing factors in primary school-aged children in Indonesia, a sun-rich country
Annals of Pediatirc Endocrinology & Metabolism
2021 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0