지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.6
- 수록면
- 434 - 439 (6page)
이용수
초록· 키워드
오류제보하기
Gestational diabetes mellitus (GDM), one of the common metabolic disorders of pregnancy, leads to functional alterations in various cells including stem cells as well as some abnormalities in fetal development. Perivascular stem cells (PVCs) have gained more attention in recent years, for the treatment of various diseases. However, the effect of GDM on PVC function has not been investigated. In our study, we isolated PVCs from umbilical cord of normal pregnant women and GDM patients and compared their phenotypes and function. There is no significant difference in phenotypic expression, response to bFGF exposure and adipogenic differentiation capacity between normal (N)-PVCs and GDM-PVCs. However, when compared with N-PVCs, early passage GDM-PVCs displayed decreased initial rates of cell yield and prolifer-ation as well as a reduced ability to promote wound closure. These results suggest that maternal metabolic dysregulation during gestation can alter the function of endogenous multipotent stem cells, which may impact their therapeutic effectiveness.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Acosta, J. C. / 2011 / Gestational diabetes mellitus alters maternal and neonatal circulating endothelial progenitor cell subsets / Am. J. Obstet. Gynecol 204:254.e8~254 e15
안보림 / 2015 / Supplementation of Growth Differentiation Factor-5 Increases Proliferation and Size of Chondrogenic Pellets of Human Umbilical Cord-Derived Perivascular Stem Cells / 조직공학과 재생의학 12(3):181~187
An, B. / 2015 / Non-enzymatic isolation followed by supplementation of basic fibroblast growth factor improves proliferation, clonogenic capacity and SSEA-4 expression of perivascular cells from human umbilical cord / Cell Tissue Res 359:767~777
Buchanan, T. A. / 2012 / Gestational diabetes mellitus: risks and management during and after pregnancy / Nat. Rev. Endocrinol 8:639~649
Buemi, M. / 2007 / Concentration of circulating endothelial progenitor cells (EPC) in normal pregnancy and in pregnant women with diabetes and hypertension / Am. J. Obstet. Gynecol 196:e61~e66
안보림 / 2015 / Supplementation of Growth Differentiation Factor-5 Increases Proliferation and Size of Chondrogenic Pellets of Human Umbilical Cord-Derived Perivascular Stem Cells / 조직공학과 재생의학 12(3):181~187
An, B. / 2015 / Non-enzymatic isolation followed by supplementation of basic fibroblast growth factor improves proliferation, clonogenic capacity and SSEA-4 expression of perivascular cells from human umbilical cord / Cell Tissue Res 359:767~777
Buchanan, T. A. / 2012 / Gestational diabetes mellitus: risks and management during and after pregnancy / Nat. Rev. Endocrinol 8:639~649
Buemi, M. / 2007 / Concentration of circulating endothelial progenitor cells (EPC) in normal pregnancy and in pregnant women with diabetes and hypertension / Am. J. Obstet. Gynecol 196:e61~e66
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
러시아 PVC 및 PVC 필름 시장동향
포장계
2017 .01
-
폐플라스틱으로부터 PVC 성분을 선택적으로 분리하기 위한 하이브리드 기술 개발 기초 연구
한국대기환경학회 학술대회논문집
2015 .11
-
PVC-Zeolite 복합체에 의한 수용액 중의 Sr 이온과 Cs 이온의 제거
한국환경과학회지
2015 .09
-
High early pregnancy serum 25-hydroxy vitamin D level, within a sub-optimal range, is associated with gestational diabetes mellitus: a prospective cohort study
Nutrition Research and Practice
2022 .02
-
High early pregnancy serum 25-hydroxy vitamin D level, within a sub-optimal range, is associated with gestational diabetes mellitus: a prospective cohort study
Nutrition Research and Practice
2022 .02
-
GDMS 분석 시 알루미늄산화물 분말 분석을 위한 시편 설계
한국분석과학회 학술대회
2016 .11
-
The RUNX1 Enhancer Element eR1: A Versatile Marker for Adult Stem Cells
Molecules and Cells
2020 .01
-
폴리염화비닐의 최근 동향
포장계
2019 .01
-
IT-기반의 임신성 당뇨병 영양관리 프로그램 개발을 위한 요구도 조사
대한지역사회영양학회지
2017 .06
-
Characterizing Organelles in Live Stem Cells Using Label-Free Optical Diffraction Tomography
Molecules and Cells
2021 .11
-
Effects of vitamin D supplementation on metabolic indices and hs-CRP levels in gestational diabetes mellitus patients : a randomized, double-blinded, placebo-controlled clinical trial
Nutrition Research and Practice
2016 .06
-
Effects of vitamin D supplementation on metabolic indices and hs-CRP levels in gestational diabetes mellitus patients : a randomized, double-blinded, placebo-controlled clinical trial
Nutrition Research and Practice
2016 .06
-
육가크롬 측정을 위한 PVC 기반 재료 제조 및 시험 평가
한국분석과학회 학술대회
2023 .05
-
Role of non-thermal atmospheric pressure bio-compatible plasma on human stem cells
한국진공학회 학술발표회초록집
2017 .02
-
Method optimization for accurate determination of thirteen phthalates in PVC via gas chromatography using D-labeled internal standard
한국분석과학회 학술대회
2022 .05
-
Directed Differentiation of Pluripotent Stem Cells by Trascription Factors
Molecules and Cells
2019 .01
-
MicroRNA-126은 난소 종양세포의 줄기세포 전사인자 (Sox2와 Lin28) 발현을 조절한다
대한임상검사과학회지
2015 .01
-
Differentiation of mesenchymal stem cells on nanopillar/pit array structures
한국진공학회 학술발표회초록집
2017 .02
-
Determination of lead, cadmium and arsenic from PVC food packaging materials by inductively coupled plasma mass spectrometry
한국분석과학회 학술대회
2016 .11
-
Migration of ESBO from food-grade PVC film into food simulants
한국분석과학회 학술대회
2015 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0