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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.2
- 수록면
- 626 - 636 (11page)
- DOI
- https://doi.org/10.1016/j.net.2020.07.010
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초록· 키워드
오류제보하기
Boroneneutron capture therapy (BNCT) is a cancer treatment method that exploits the high neutronreactivity of boron. Monitoring the prompt gamma rays (PGs) produced during neutron irradiation isessential for ensuring the accuracy and safety of BNCT. We investigate the imaging of PGs produced bythe boroneneutron capture reaction through Monte Carlo simulations of a gamma camera with a SrI2scintillator and parallel-hole collimator. GAGG scintillator is also used for a comparison. The simulationsallow the shapes of the energy spectra, which exhibit a peak at 478 keV, to be determined along with thePG images from a boronewater phantom. It is found that increasing the size of the water phantomresults in a greater number of image counts and lower contrast. Additionally, a higher septal penetrationratio results in poorer image quality, and a SrI2 scintillator results in higher image contrast. Thus, we cansimulate the BNCT process and obtain an energy spectrum with a reasonable shape, as well as suitable PGimages. Both GAGG and SrI2 crystals are suitable for PG imaging during BNCT. However, for higher imagingquality, SrI2 and a collimator with a lower septal penetration ratio should be utilized.
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참고문헌 (29)
참고문헌 신청
R. L. Moss / 2014 / Critical review, with an optimistic outlook, on boron neutron capture therapy (BNCT) / Appl. Radiat. Isot 88:2~11
L. Kankaanranta / 2012 / Boron neutron capture therapy in the treatment of locally recurred head and neck cancer: final analysis of a phase I/II trial / Int. J. Radiat. Oncol. Biol. Phys 82:e67~e75
R. F. Barth / 2012 / Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer / Radiat. Oncol 7:146~167
S. Savolainen / 2013 / Boron neutron capture therapy(BNCT)in Finland : technological and physical prospects after 20 years of experiences / Phys. Med 29:233~248
T. Kobayashi / 2000 / A noninvasive dose estimation system for clinical BNCT based on PG-SPECT-Conceptual study and fundamental experiments using HPGe and CdTe semiconductor detectors / Med. Phys 27:2124~2132
L. Kankaanranta / 2012 / Boron neutron capture therapy in the treatment of locally recurred head and neck cancer: final analysis of a phase I/II trial / Int. J. Radiat. Oncol. Biol. Phys 82:e67~e75
R. F. Barth / 2012 / Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer / Radiat. Oncol 7:146~167
S. Savolainen / 2013 / Boron neutron capture therapy(BNCT)in Finland : technological and physical prospects after 20 years of experiences / Phys. Med 29:233~248
T. Kobayashi / 2000 / A noninvasive dose estimation system for clinical BNCT based on PG-SPECT-Conceptual study and fundamental experiments using HPGe and CdTe semiconductor detectors / Med. Phys 27:2124~2132
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