지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.2
- 수록면
- 20 - 24 (5page)
- DOI
- 10.5125/jkaoms.2021.47.1.20
이용수
초록· 키워드
오류제보하기
Objectives: The aim of this study was to evaluate the profile of patients on antiresorptive therapies for cancer treatment and assess presence of oral lesions, oral hygiene status, and knowledge regarding medication-related osteonecrosis of the jaw (MRONJ).
Materials and Methods: This was an observational cross-sectional study that evaluated patients treated with antiresorptive medication at a single cancer hospital. Clinical data were collected and oral examination was performed to assess patient oral health.
Results: From July 2017 to December 2018, 90 patients were assessed; 64 were female and 26 were male, and the mean age was 61 years. The most common drug was an intravenous bisphosphonate, zoledronic acid. Among the 90 patients, 47 presented with some type of oral disease, isolated or associated.
Among these 47 patients, 9 patients (10%) developed osteonecrosis. Oral hygiene was evaluated, and most patients, with or without MRONJ, presented with regular to poor condition. Regarding patient knowledge of the risks of MRONJ and the risks associated with dental surgery, 60% stated that they were not aware of the risks.
Conclusion: Identifying the profile of patients and their needs facilitates not only the preventive process, but also the emergence of new therapeutic options. Our study shows that most patients are weakened both by metastatic disease and antineoplastic treatment as well as by issues associated with aging because most were over 60 years of age. Collectively, this information should be considered for management of preventive and therapeutic measures.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Ourania Nicolatou-Galitis / 2019 / Medication-related osteonecrosis of the jaw: definition and best practice for prevention, diagnosis, and treatment / Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 127(2):117~135
Coleman RE. / 1997 / Skeletal complications of malignancy / Cancer 80(8 Suppl):1588~1594
Onur Şahin / 2019 / Risk factors of medication-related osteonecrosis of the jaw: a retrospective study in a Turkish subpopulation / 대한구강악안면외과학회지 45(2):108~115
Salvatore L. Ruggiero / 2014 / American Association of Oral and Maxillofacial Surgeons Position Paper on Medication-Related Osteonecrosis of the Jaw—2014 Update / Journal of Oral and Maxillofacial Surgery 72(10):1938~1956
Antonio Fabrizio Nifosì / 2019 / Osteonecrosis of the jaw in the era of targeted therapy and immunotherapy in oncology / 대한구강악안면외과학회지 45(1):3~8
Coleman RE. / 1997 / Skeletal complications of malignancy / Cancer 80(8 Suppl):1588~1594
Onur Şahin / 2019 / Risk factors of medication-related osteonecrosis of the jaw: a retrospective study in a Turkish subpopulation / 대한구강악안면외과학회지 45(2):108~115
Salvatore L. Ruggiero / 2014 / American Association of Oral and Maxillofacial Surgeons Position Paper on Medication-Related Osteonecrosis of the Jaw—2014 Update / Journal of Oral and Maxillofacial Surgery 72(10):1938~1956
Antonio Fabrizio Nifosì / 2019 / Osteonecrosis of the jaw in the era of targeted therapy and immunotherapy in oncology / 대한구강악안면외과학회지 45(1):3~8
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