지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.2
- 수록면
- 1 - 9 (9page)
- DOI
- 10.3803/EnM.2023.103
이용수
초록· 키워드
오류제보하기
To maintain normal glucose homeostasis after a meal, it is essential to secrete an adequate amount of insulin from pancreatic β-cells. However, if pancreatic β-cells solely depended on the blood glucose level for insulin secretion, a surge in blood glucose levels would be inevitable after the ingestion of a large amount of carbohydrates. To avoid a deluge of glucose in the bloodstream after a large carbohydrate- rich meal, enteroendocrine cells detect the amount of nutrient absorption from the gut lumen and secrete incretin hormones at scale. Since insulin secretion in response to incretin hormones occurs only in a hyperglycemic milieu, pancreatic β-cells can secrete a “Goldilocks” amount of insulin (i.e., not too much and not too little) to keep the blood glucose level in the normal range. In this regard, pancreatic β-cell sensitivity to glucose and incretin hormones is crucial for maintaining normal glucose homeostasis. In this Namgok lecture 2022, we review the effects of current anti-diabetic medications on pancreatic β-cell sensitivity to glucose and incretin hormones.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Incretin Hormones: Pathophysiological Risk Factors and Potential Targets for Type 2 Diabetes
Journal of Obesity & Metabolic Syndrome
2021 .09
-
In Vivo Models for Incretin Research: From the Intestine to the Whole Body
Endocrinology and Metabolism
2016 .01
-
The Insulin Resistance but Not the Insulin Secretion Parameters Have Changed in the Korean Population during the Last Decade
Diabetes and Metabolism Journal
2015 .01
-
Identification of sphingosine 1-phosphate level and MAPK/ERK signaling in pancreatic β cells
Annals of Pediatirc Endocrinology & Metabolism
2021 .12
-
Self-Monitoring of Blood Glucose in Patients with Insulin-Treated Type 2 Diabetes Mellitus
Diabetes and Metabolism Journal
2018 .01
-
Role of Salt Inducible Kinases in the Control of Glucose Homeostasis
한국실험동물학회 학술발표대회 논문집
2015 .08
-
Assessment of Insulin Secretion and Insulin Resistance in Human
Diabetes and Metabolism Journal
2021 .09
-
비만을 동반한 제 2형 당뇨병환자의 혈당 조절을 위한 운동 중재 : 체계적 문헌고찰
대한물리의학회지
2018 .01
-
혈당 조절 프로토콜 적용에 따른 흉부외과 중환자의 혈당 조절 상태와 혈당 변동
중환자간호학회지
2015 .12
-
Association Analysis between Genes’ Variants for Regulating Mitochondrial Dynamics and Fasting Blood Glucose Level
대한의생명과학회지
2016 .09
-
Regulation of Pancreatic β-Cell Mass by Gene-Environment Interaction
Diabetes and Metabolism Journal
2022 .01
-
Lithium and exercise ameliorate insulin-deficient hyperglycemia by independently attenuating pancreatic α-cell mass and hepatic gluconeogenesis
The Korean Journal of Physiology & Pharmacology
2024 .01
-
Normal Glucose Tolerance with a High 1-Hour Postload Plasma Glucose Level Exhibits Decreased β-Cell Function Similar to Impaired Glucose Tolerance (Diabetes Metab J 2015;39:147-53)
Diabetes and Metabolism Journal
2015 .01
-
Understanding of type 1 diabetes mellitus: what we know and where we go
Clinical and Experimental Pediatrics
2018 .01
-
Regulating long-term blood glucose level of type 1 diabetes mouse by transplantation of hydrogel nanofilm encapsulated pancreatic β-cell spheroids
한국실험동물학회 학술발표대회 논문집
2022 .01
-
당류유형이 혈당변화에 미치는 효과
근관절건강학회지
2019 .12
-
In Vivo and In Vitro Quantification of Glucose Kinetics: From Bedside to Bench
Endocrinology and Metabolism
2020 .01
-
삼채(Allium Hookeri)의 급여가 당뇨마우스의 당질 대사에 미치는 영향
생약학회지(Korean Journal of Pharmacognosy)
2015 .03
-
유기인계 중독환자에서 내원시 혈당과 예후와의 연관성
대한임상독성학회지
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0