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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2025.2
- 수록면
- 129 - 133 (5page)
- DOI
- 10.9721/KJFST.2025.57.1.129
이용수
초록· 키워드
오류제보하기
Horse oil contains up to 65% unsaturated fatty acids and protects human skin from environmental stressors. This study was performed to investigate the stability and protective effects of nano-sized horse oil-in-water (HO/W) emulsions, including emulsions enhanced with α-tocopherol (HO/W+α-T) or trolox (HO/W+T), against particulate matter (PM)-induced oxidative stress in HaCaT human keratinocytes. Mean particle diameters in these HO/W emulsions ranged from 154.5 to 169.2 nm, classifying them as nano-sized emulsions. The encapsulation efficiencies of HO/W and HO/W+α-T were 89.98-90.79%. The HO/W, HO/W+α-T, and HO/W+T emulsions sufficiently reduced lactate hydrogenase (LDH) release in HaCaT cells that has been exposed to 62.5 mg/mL of PM. The HO/W+α-T emulsion also significantly inhibited PM-induced lipid peroxidation. These results demonstrate that the horse oil O/W emulsion exhibits cytoprotective effects by inhibiting lipid peroxidation and increasing the viability of PM-exposed HaCaT cells, suggesting its potential as a novel strategy for preventing skin damage caused by environmental pollutants.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Conclusion
References
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