개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 36 - 42 (7page)
이용수
초록· 키워드
오류제보하기
Bioactive calcium phosphate ceramics, such as hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), have been considered for use as synthetic bone graft substitutes in regenerative surgeries. However, the rate of bioresorption of β-TCP is unpredictable. In order to resolve the drawbacks of β-TCP, coatings of bioactive materials on the apatite graft base materials were introduced. Magnesium (Mg) plays a crucial role in cell proliferation and function. Cells are unable to proliferate in the absence of extracellular Mg because of the resultant reduction in DNA, RNA and protein synthesis. This study was performed to evaluate early osteoblastic cell responses to Mg coated β-TCP surfaces. The bioactive surfaces on β-TCP base were developed by radio frequency (RF) magnetron coating method. Thin Mg coating on β-TCP substrates was performed. Surface characteristics were evaluated by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX). The bioactivity of coated surfaces was also evaluated by SEM and cell proliferation. The disks were divided into 2 groups: control group (TCP) and test group (TCP-Mg). SEM and EDX analysis showed that Mg deposition on the β-TCP substrates were performed successfully. Under SEM, no significant difference in cell morphology was observed between the TCP and TCP-Mg groups. In the MTT assay, the TCP-Mg group had significantly better cellular responses with regard to proliferation at 5 days (p<0.05). Within certain limitations, the results of this study suggests that Mg coatings on β-TCP offers great potential as a graft material for hard tissue regeneration.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Yaszemski MJ / 1996 / Evolution of bone transplantation : molecular, cellular and tissue strategies to engineer human bone / Biomaterials 17:175~185
Galindo-Moreno P / 2013 / Slow resorption of anorganic bovine bone by osteoclasts in maxillary sinus augmentation / Clin Implant DentRel Res 15:858~866
Fan H / 2007 / Surface structural biomimetics and the osteoinduction of calcium phosphate materials / J Nanoscience Nanotechnol 7:808~813
Ohsawa K / 2000 / The expression of bone matrix protein mRNAs around beta-TCP particles implanted into bone / J Biomed Mater Res 52:460~466
Ohura K / 1996 / Resorption of, and bone formation from, new beta-tricalcium phosphate-monocalcium phosphate cements:an in vivo study / J Biomed Mater Res 30:193~200
Galindo-Moreno P / 2013 / Slow resorption of anorganic bovine bone by osteoclasts in maxillary sinus augmentation / Clin Implant DentRel Res 15:858~866
Fan H / 2007 / Surface structural biomimetics and the osteoinduction of calcium phosphate materials / J Nanoscience Nanotechnol 7:808~813
Ohsawa K / 2000 / The expression of bone matrix protein mRNAs around beta-TCP particles implanted into bone / J Biomed Mater Res 52:460~466
Ohura K / 1996 / Resorption of, and bone formation from, new beta-tricalcium phosphate-monocalcium phosphate cements:an in vivo study / J Biomed Mater Res 30:193~200
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Epigallocatechin-3-gallate 함유 β-TCP이식재의 골재생능에 관한 조직계측학적 평가
대한치과재료학회지
2018 .09
-
불안정성 전자간부 골절의 활강 압박 고 나사 수술적 고정술에 있어 베타 3칼슘 인산염 이식의 역할
대한골절학회지
2016 .01
-
The Influences of Different Ratios of Biphasic Calcium Phosphate and Collagen Augmentation on Posterior Lumbar Spinal Fusion in Rat Model
Yonsei Medical Journal
2017 .01
-
Effects of micro-porosity and local BMP-2 administration on bioresorption of β-TCP and new bone formation
생체재료학회지
2019 .01
-
Comparative studies on thin polycaprolactone-tricalcium phosphate composite scaffolds and its interaction with mesenchymal stem cells
생체재료학회지
2019 .01
-
Late-term healing in an augmented sinus with different ratios of biphasic calcium phosphate: a pilot study using a rabbit sinus model
Journal of Periodontal & Implant Science
2016 .01
-
Beta-Tricalcium Phosphate Block for Donor Site Morbidity of the Patella in Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Graft
Knee Surgery and Related Research
2019 .01
-
Sinus augmentation with poly(ε) caprolactone-β tricalcium phosphate scaffolds, mesenchymal stem cells and platelet rich plasma for one-stage dental implantation in minipigs
Journal of Periodontal & Implant Science
2023 .06
-
Remineralization ability of fluoride varnish containing tricalcium phosphate by time
대한구강보건학회지
2017 .03
-
Efficacy and safety of rhBMP/β-TCP in alveolar ridge preservation: a multicenter, randomized, open-label, comparative, investigator-blinded clinical trial
Maxillofacial Plastic Reconstructive Surgery
2021 .12
-
Biosilicated collagen/β-tricalcium phosphate composites as a BMP-2-delivering bone-graft substitute for accelerated craniofacial bone regeneration
생체재료학회지
2021 .01
-
Erratum : Evaluation of the clinical and radiographic effectiveness of treating peri-implant bone defects with a new biphasic calcium phosphate bone graft: a prospective, multicenter randomized controlled trial
Journal of Periodontal & Implant Science
2024 .06
-
Osteogenic differentiation of preosteoblast on the amine plasma-polymerized 3D PCL/β-TCP scaffold
대한치과재료학회 학술대회
2021 .11
-
α-TCP를 첨가한 글라스 아이오노머 시멘트의 법랑질 탈회저항성
대한치과재료학회지
2015 .06
-
In vitro and in vivo analyses of the biocompatibility of sintered TCP-HA composite screws
Oral Biology Research
2022 .12
-
표준화 환자를 이용한 전문심장처치술 교육 이수자들의 심율동전환과 경피심박조율처치 능력 평가
대한응급의학회지
2015 .01
-
치주 조직 재생을 위한 3D 프린터로 제작된 흡수성 차폐막의 물리적 및 생분해성 특성
대한치과재료학회지
2021 .06
-
Material characteristics and biocompatibility of a β-tricalcium phosphate/polycaprolactone composite scaffold for bone regeneration
대한치과재료학회 학술대회
2015 .11
-
Assessment of stem cell viability in the initial healing period in rabbits with a cranial bone defect according to the type and form of scaffold
Journal of Periodontal & Implant Science
2019 .01
-
과루인 및 과루인청혈플러스가 인간 탯줄 정맥 내피 세포(Human umbilicl vein endothelial cells, HUVECs)에서 염증인자 발현 억제에 미치는 영향
대한한방내과학회지
2022 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0