지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제49권 제2호
- 발행연도
- 2019.1
- 수록면
- 114 - 126 (13page)
이용수
초록· 키워드
오류제보하기
Purpose The aim of this study was to evaluate the enhancement of osteogenic potential of biphasic calcium phosphate (BCP) bone substitute coated with Escherichia coli-derived recombinant human bone morphogenetic protein-2 (ErhBMP-2) and epigallocatechin-3-gallate (EGCG). Methods The cell viability, differentiation, and mineralization of osteoblasts was tested with ErhBMP-2-/EGCG solution. Coated BCP surfaces were also investigated. Standardized, 6-mm diameter defects were created bilaterally on the maxillary sinus of 10 male New Zealand white rabbits. After removal of the bony windows and elevation of sinus membranes, ErhBMP-2-/EGCG-coated BCP was applied on one defect in the test group. BCP was applied on the other defect to form the control group. The animals were sacrificed at 4 or 8 weeks after surgery. Histologic and histometric analyses of the augmented graft and surrounding tissue were performed. Results The 4-week and 8-week test groups showed more new bone (%) than the corresponding control groups (P<0.05). The 8-week test group showed more new bone (%) than the 4-week test group (P<0.05). Conclusions ErhBMP-2-/EGCG-coated BCP was effective as a bone graft material, showing enhanced osteogenic potential and minimal side effects in a rabbit sinus augmentation model.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Bessho K / 2000 / Bone induction by Escherichia coli-derived recombinant human bone morphogenetic protein-2 compared with Chinese hamster ovary cell-derived recombinant human bone morphogenetic protein-2 / Br J Oral Maxillofac Surg 38:645~649
Lee JH / 2010 / The induction of bone formation in rat calvarial defects and subcutaneous tissues by recombinant human BMP-2, produced in Escherichia coli / Biomaterials 31:3512~3519
Long S / 2006 / Expression, purification, and renaturation of bone morphogenetic protein-2 from Escherichia coli / Protein Expr Purif 46:374~378
Vallejo LF / 2002 / Renaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli / J Biotechnol 94:185~194
최경희 / 2008 / E. coli 발현 시스템에 의해 생산된 recombinant human bone morphogenetic protein-2의 정제와 생물학적 활성 / Journal of Periodontal & Implant Science 38(1):41~50
Lee JH / 2010 / The induction of bone formation in rat calvarial defects and subcutaneous tissues by recombinant human BMP-2, produced in Escherichia coli / Biomaterials 31:3512~3519
Long S / 2006 / Expression, purification, and renaturation of bone morphogenetic protein-2 from Escherichia coli / Protein Expr Purif 46:374~378
Vallejo LF / 2002 / Renaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli / J Biotechnol 94:185~194
최경희 / 2008 / E. coli 발현 시스템에 의해 생산된 recombinant human bone morphogenetic protein-2의 정제와 생물학적 활성 / Journal of Periodontal & Implant Science 38(1):41~50
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Clinical efficacy of amniotic membrane with biphasic calcium phosphate in guided tissue regeneration of intrabony defects- a randomized controlled clinical trial
생체재료학회지
2021 .01
-
Bioactive calcium phosphate materials and applications in bone regeneration
생체재료학회지
2019 .01
-
Influence of biodegradable polymer membrane on new bone formation and biodegradation of biphasic bone substitutes: an animal mandibular defect model study
Maxillofacial Plastic Reconstructive Surgery
2020 .01
-
Effectiveness of biphasic calcium phosphate block bone substitutes processed using a modified extrusion method in rabbit calvarial defects
Journal of Periodontal & Implant Science
2015 .01
-
New processing and applications of Calcium Phosphate Cements for bone augmentation
대한치과재료학회 학술대회
2015 .04
-
Combined effects of a chemically cross-linked porcine collagen membrane and highly soluble biphasic calcium phosphate on localized bone regeneration
대한치과의사협회지
2018 .11
-
요추부 후측방 유합술시 자가 골수와 국소 자가골 및 이상인산칼슘 혼합 이식술의 골유합율
대한척추외과학회지
2015 .01
-
Four-week histologic evaluation of grafted calvarial defects with adjunctive hyperbaric oxygen therapy in rats
Journal of Periodontal & Implant Science
2016 .01
-
Long and Short Range Order Structural Analysis of In-situ Formed Biphasic Calcium Phosphates
생체재료학회지
2015 .09
-
Three-dimensionally printed biphasic calcium phosphate blocks with different pore diameters for regeneration in rabbit calvarial defects
생체재료학회지
2022 .09
-
Comparative evaluation of biphasic calcium phosphate and biphasic calcium phosphate collagen composite on osteoconductive potency in rabbit calvarial defect
생체재료학회지
2015 .03
-
Review of bone graft and bone substitutes with an emphasis on fracture surgeries
생체재료학회지
2019 .01
-
Epigallocatechin-3-gallate 함유 β-TCP이식재의 골재생능에 관한 조직계측학적 평가
대한치과재료학회지
2018 .09
-
콜라겐 유도 관절염 모델에서 동반된 치주염 유발시 EGCG가 치주염 치료에 미치는 효과에 관한 연구
대한치과의사협회지
2016 .04
-
골 대체물 및 골 치유 촉진에 대한 발전
대한골절학회지
2017 .01
-
Effect of Extraction Conditions of Green Tea on Antioxidant Activity and EGCG Content: Optimization using Response Surface Methodology
Natural Product Sciences
2016 .12
-
타이타늄 표면에 코팅된 epigallocatechin gallate의 사람치수세포 분화 촉진
대한치과재료학회지
2015 .09
-
요추부 후측방 유합술 시 국소 자가골 및 골 이식 대체재 혼합 이식에 의한 골유합률의 비교
대한정형외과학회지
2020 .04
-
A comparative study of bone regeneration by the combination of biphasic calcium phosphate alloplast and barrier membrane on rat calvarial defect model
한국실험동물학회 학술발표대회 논문집
2019 .01
-
Biosilicated collagen/β-tricalcium phosphate composites as a BMP-2-delivering bone-graft substitute for accelerated craniofacial bone regeneration
생체재료학회지
2021 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0