지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 301 - 307 (7page)
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초록· 키워드
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Background and Purpose During transient global amnesia (TGA), selective impairment of episodic memory is assumed to occur due to alteration in the neuronal network between the hippocampus and parietooccipital cortices that also include a hub for smooth pursuit (SP) eye movements. This study aimed to determine whether SP is impaired during TGA, and to identify any anatomical and functional linkage present between the oculomotor and memory systems. Methods Within a median of 1.0 day of TGA, horizontal SP was evaluated in 145 patients with a target moving at peak velocities of 10°/s and 20°/s. The average SP gains of patients were compared with those of the age-matched controls. Results The patients with TGA showed lower SP gains in both directions for both peak target velocities. While the normal controls showed symmetric SP in the rightward and leftward directions, in the TGA patients the SP gain was lower during rightward than leftward SP regardless of bilaterality or the side of the lesions. Conclusions The cortical regions processing information about visual motion appeared to be affected during or soon after an amnestic episode of TGA, and more so in the right hemisphere. This means that disturbed processing of dynamic visual information may be related to the impaired spatial orientation observed during TGA
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참고문헌 (31)
참고문헌 신청
Hodges JR / 1990 / Syndromes of transient amnesia: towards a classification. A study of 153 cases / J Neurol Neurosurg Psychiatry 53:834~843
Bartsch T / 2010 / Transient global amnesia : functional anatomy and clinical implications / Lancet Neurol 9:205~214
Burwell RD / 2000 / The parahippocampal region : corticocortical connectivity / Ann N Y Acad Sci 911:25~42
Libby LA / 2012 / Differential connectivity of perirhinal and parahippocampal cortices within human hippocampal subregions revealed by high-resolution functional imaging / J Neurosci 32:6550~6560
Ranganath C / 2012 / Two cortical systems for memory-guided behaviour / Nat Rev Neurosci 13:713~726
Bartsch T / 2010 / Transient global amnesia : functional anatomy and clinical implications / Lancet Neurol 9:205~214
Burwell RD / 2000 / The parahippocampal region : corticocortical connectivity / Ann N Y Acad Sci 911:25~42
Libby LA / 2012 / Differential connectivity of perirhinal and parahippocampal cortices within human hippocampal subregions revealed by high-resolution functional imaging / J Neurosci 32:6550~6560
Ranganath C / 2012 / Two cortical systems for memory-guided behaviour / Nat Rev Neurosci 13:713~726
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