지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 152 - 157 (6page)
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초록· 키워드
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Objectives: The number of elderly patients with systemic basal disease requiring invasive dental treatment has increased. Appropriate prediction of surgical invasiveness and combined use of psychosedation are thought to contribute to safe whole-body management. Dexmedetomidine (DEX) exhibits analgesic and anti-anxiolytic properties and causes mild respiratory depression. Studies regarding DEX use in elderly non-intubated patients are scarce. We aimed to use retrospective data to determine an effective dose of DEX to induce adequate sedation in elderly patients undergoing invasive dental surgery under local anesthesia. Materials and Methods: One hundred two patients aged 70 to 96 years were presumably appropriately controlled with sedation. DEX was administered at an initial loading dose of 2.0 to 3.1 μg/kg/hr for 10 minutes. We divided the patients into five groups by age and compared their blood pressures and heart rates. Results: In all five groups, blood pressure decreased suddenly at approximately 15 and 20 minutes after DEX administration. A marked decrease in blood pressure was noted in patients aged 75 to 79 years. Conclusion: For elderly patients aged 75 years and above, the initial loading dose of DEX needs to be reduced to lower than half that required for young and middle-age adults.
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등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Cormack JR / 2005 / The role of alpha2-agonists in neurosurgery / J Clin Neurosci 12:375~378
Ebert TJ / 2000 / The effects of increasing plasma concentrations of dexmedetomidine in humans / Anesthesiology 93:382~394
Constantin JM / 2016 / Efficacy and safety of sedation with dexmedetomidine in critical care patients : a meta-analysis of randomized controlled trials / Anaesth Crit Care Pain Med 35:7~15
Cillo JE Jr / 2006 / Hemodynamics in elderly coronary artery disease patients undergoing propofol sedation / J Oral Maxillofac Surg 64:1338~1342
Taguchi T / 2011 / Intravenous sedation and hemodynamic changes during dental implant surgery / Int J Oral Maxillofac Implants 26:1303~1308
Ebert TJ / 2000 / The effects of increasing plasma concentrations of dexmedetomidine in humans / Anesthesiology 93:382~394
Constantin JM / 2016 / Efficacy and safety of sedation with dexmedetomidine in critical care patients : a meta-analysis of randomized controlled trials / Anaesth Crit Care Pain Med 35:7~15
Cillo JE Jr / 2006 / Hemodynamics in elderly coronary artery disease patients undergoing propofol sedation / J Oral Maxillofac Surg 64:1338~1342
Taguchi T / 2011 / Intravenous sedation and hemodynamic changes during dental implant surgery / Int J Oral Maxillofac Implants 26:1303~1308
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