지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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The hallmark symptom of sarcopenia is the loss of muscle mass and strength without the loss of overall body weight. Sarcopenia patients are likely to have worse clinical outcomes and higher mortality than do healthy individuals. The sarcopenia population shows an annual increase of ~0.8% in the population after age 50, and the prevalence rate is rapidly increasing with the recent worldwide aging trend. Based on International Classification of Diseases, Tenth Revision, a global classification of disease published by the World Health Organization, issued the disease code (M62.84) given to sarcopenia in 2016. Therefore, it is expected that the study of sarcopenia will be further activated based on the classification of disease codes in the aging society. Several epidemiological studies and meta-analyses have looked at the correlation between the prevalence of sarcopenia and several environmental factors. In addition, studies using cell lines and rodents have been done to understand the biological mechanism of sarcopenia. Laboratory rodent models are widely applicable in sarcopenia studies because of the advantages of time savings, cost saving, and various analytical applications that could not be used for human subjects. The rodent models that can be applied to the sarcopenia research are diverse, but a simple and fast method that can cause atrophy or aging is preferred. Therefore, we will introduce various methods of inducing muscular atrophy in rodent models to be applied to the study of sarcopenia.
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등록된 정보가 없습니다.
참고문헌 (103)
참고문헌 신청
Rosenberg IH / 1989 / Summary comments / Am J Clin Nutr 50:1231~1233
Janssen I / 2010 / Evolution of sarcopenia research / Appl Physiol Nutr Metab 35:707~712
Lloyd N / AIM coalition announces establishment of ICD-10-CM code for sarcopenia by the centers for disease control and prevention
Melton LJ 3rd / 2000 / Epidemiology of sarcopenia / J Am Geriatr Soc 48:625~630
Abellan van Kan G / 2009 / Epidemiology and consequences of sarcopenia / J Nutr Health Aging 13:708~712
Janssen I / 2010 / Evolution of sarcopenia research / Appl Physiol Nutr Metab 35:707~712
Lloyd N / AIM coalition announces establishment of ICD-10-CM code for sarcopenia by the centers for disease control and prevention
Melton LJ 3rd / 2000 / Epidemiology of sarcopenia / J Am Geriatr Soc 48:625~630
Abellan van Kan G / 2009 / Epidemiology and consequences of sarcopenia / J Nutr Health Aging 13:708~712
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