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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 398 - 405 (8page)
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초록· 키워드
오류제보하기
Egg allergy has been shown to be the most common food allergy in children with atopic dermatitis. Allergic reactions to proteins derived from egg white (EW) are more common than those derived from egg yolk. Ovomucoid, ovalbumin, ovotransferrin, and lysozyme have been identified as major allergens in EW. This study was conducted to evaluate the effect of EW on immune modulation in an induced allergy mouse model. A total of 50 five-week-old BALB/c male mice were treated with trimellitic anhydride (TMA) for three weeks to induce allergy-like symptoms. The TMA-treated mice were rested for one week and then divided into five groups and fed 0, 10, 50, and 100 mg/d EW for four weeks. All EW consumption groups showed no significant increase or decrease in the populations of white blood cells; however, a significant increase in B-lymphocyte activity was observed in the fourth week. Furthermore, EW consumption did not influence serum immunoglobulin G and immunoglobulin E levels. Taken together, these data demonstrate that the consumption of EW by TMA-treated mice did not increase allergic parameters such as serum IgE level, but enhanced the lymphocyte activities against pathogens. Therefore, this study suggests that the consumption of EW promotes Th2 immune modulation, and EW could be an excellent candidate for maintaining health.
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등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Abbas, A. K. / 1996 / Functional diversity of helper T lymphocytes / Nature 383:787~793
Anet, J. / 1985 / Allergens in the white and yolk of hen’s egg. A study of IgE binding by egg proteins / Int. Arch. Allergy Appl. Immunol 77:364~371
Bernhisel-Broadbent, J. / 1994 / Allergenicity and antigenicity of chicken egg mucoid (Gal d III) compared with ovalbumin (Gal d I) in children with egg allergy and in mice / J. Allergy Clin. Immunol 93:1047~1059
Bernstein, D. I. / 1982 / Clinical and immunologic evaluation of trimellitic anhydride- and phthalic anhydride-exposed workers using a questionnaire with comparative analysis of enzyme-linked immunosorbent and radioimmunoassay studies / J. Allergy Clin. Immunol 69:311~318
Böhm, I. / 1997 / Th1 cells, Th2 cells and atopic dermatitis / Hautarzt 48:223~227
Anet, J. / 1985 / Allergens in the white and yolk of hen’s egg. A study of IgE binding by egg proteins / Int. Arch. Allergy Appl. Immunol 77:364~371
Bernhisel-Broadbent, J. / 1994 / Allergenicity and antigenicity of chicken egg mucoid (Gal d III) compared with ovalbumin (Gal d I) in children with egg allergy and in mice / J. Allergy Clin. Immunol 93:1047~1059
Bernstein, D. I. / 1982 / Clinical and immunologic evaluation of trimellitic anhydride- and phthalic anhydride-exposed workers using a questionnaire with comparative analysis of enzyme-linked immunosorbent and radioimmunoassay studies / J. Allergy Clin. Immunol 69:311~318
Böhm, I. / 1997 / Th1 cells, Th2 cells and atopic dermatitis / Hautarzt 48:223~227
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