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- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.5
- 수록면
- 39 - 39 (1page)
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Repetitive DNA sequences are known to occupy up to 90% of the total genome and have been treated as junk DNA for a long time, but recently found to be largely involved in gene regulation, development, differentiation, and disease development such as cancer. According to sequence characteristics, they are distributed in specific regions of the chromosomes. So, the characteristics, abundance, and distribution of the repetitive DNA provide very important information to understand the genome structure and function. Fluorescence in situ hybridization (FISH) visualize specific DNA sequences on the chromosomes and is useful to elucidate repetitive DNA composition, organization, and distribution in the genome. In silico genome-wide repeat mining was accomplished using < 1× whole-genome NGS reads through the Repeat Explorer pipeline and FISH detection was carried out using the newly mined repeat probes. Different classes of repetitive DNAs including transposable element and tandemly repeated ... 전체 초록 보기
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