지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 345 - 352 (8page)
- DOI
- 10.7783/KJMCS.2021.29.5.345
이용수
초록· 키워드
오류제보하기
Background: Many Artemisia species are used in traditional medicine to treat gastrointestinal disorders and various other ailments. However, the antioxidant and phenolic compounds present in Hallasan wormwood (Artemisia japonica var. hallaisanensis) have not been investigated yet.
Methods and Results: Extracts of Hallasan wormwood (aerial parts and roots) were extracted using methanol and sequentially treated with solvent-solvent fractionation using n-hexane, ethyl acetate, and water-saturated butanol, to yield fractions with variations in polarity. The phenolic compounds present in the extracts and fractions were determined using high performance liquid chromatography (HPLC) and colorimetry. The antioxidant activities were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, trolox equivalent antioxidant capacity (TEAC), ferric reducing antioxidant power (FRAP), and oxygen radical antioxidant capacity (ORAC) methods. The results revealed that the ethyl acetate fraction had high total phenolic and total flavonoid contents. Furthermore, the ethyl acetate fraction of roots showed the highest antioxidant activity.
Conclusions: Metanolic extracts from the roots and aerial parts of Hallasan wormwood showed different antioxidant activities; nine phenolic acids and one flavonoid were detected in Hallasan wormwood. Thus, the finding of this study provide valuable data for research on functional substances from plants.
Methods and Results: Extracts of Hallasan wormwood (aerial parts and roots) were extracted using methanol and sequentially treated with solvent-solvent fractionation using n-hexane, ethyl acetate, and water-saturated butanol, to yield fractions with variations in polarity. The phenolic compounds present in the extracts and fractions were determined using high performance liquid chromatography (HPLC) and colorimetry. The antioxidant activities were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, trolox equivalent antioxidant capacity (TEAC), ferric reducing antioxidant power (FRAP), and oxygen radical antioxidant capacity (ORAC) methods. The results revealed that the ethyl acetate fraction had high total phenolic and total flavonoid contents. Furthermore, the ethyl acetate fraction of roots showed the highest antioxidant activity.
Conclusions: Metanolic extracts from the roots and aerial parts of Hallasan wormwood showed different antioxidant activities; nine phenolic acids and one flavonoid were detected in Hallasan wormwood. Thus, the finding of this study provide valuable data for research on functional substances from plants.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (25)
참고문헌 신청
Ahmed AS / 2014 / Polarity of extracts and fractions of four Combretum(Combretaceae)species used to treat infections and gastrointestinal disorders in southern African traditional medicine has a major effect on different relevant in vitro activities / Journal of Ethnopharmacology 154:339~350
Aruoma OI / 1998 / Free radicals, oxidative stress, and antioxidants in human health and disease / Journal of the American Oil Chemists' Society 75:199~212
Balasundram N / 2006 / Phenolic compounds in plants and agri-industrial by-products : Antioxidant activity, occurrence, and potential uses / Food Chemistry 99:191~203
Blois MS / 1958 / Antioxidant determinations by the use of a stable free radical / Nature 181:1199~1200
Bravo L / 1998 / Polyphenols : Chemistry, dietary sources, metabolism, and nutritional significance / Nutrition Reviews 56:317~333
Aruoma OI / 1998 / Free radicals, oxidative stress, and antioxidants in human health and disease / Journal of the American Oil Chemists' Society 75:199~212
Balasundram N / 2006 / Phenolic compounds in plants and agri-industrial by-products : Antioxidant activity, occurrence, and potential uses / Food Chemistry 99:191~203
Blois MS / 1958 / Antioxidant determinations by the use of a stable free radical / Nature 181:1199~1200
Bravo L / 1998 / Polyphenols : Chemistry, dietary sources, metabolism, and nutritional significance / Nutrition Reviews 56:317~333
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