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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.68 No.2
- 발행연도
- 2015.1
- 수록면
- 128 - 135 (8page)
이용수
초록· 키워드
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Background: In a previous study, fluid kinetic models were applied to describe the volume expansion of the fluid spaceby administration of crystalloid and colloid solutions. However, validation of the models were not performed, it is necessaryto evaluate the predictive performance of these models in another population.
Methods: Ninety five consenting patients undergoing elective spinal surgery under general anesthesia were enrolled inthis study. These patients were randomly assigned to three fluid groups i.e. Hartmann’s solution (H group, n = 28), VoluvenⓇ (V group, n = 34), and HextendⓇ (X group, n = 33). After completion of their preparation for surgery, the patientsreceived a loading and maintenance volume of each fluid predetermined by nomograms based on fluid pharmacokineticmodels during the 60-minute use of an infusion pump. Arterial samples were obtained at preset intervals of 0, 10, 20, and30 min after fluid administration. The predictive performances of the fluid kinetic modes were evaluated using the fractionalchange of arterial hemoglobin. The relationship between blood-volume dilution and target dilution of body fluidspace was also evaluated using regression analysis.
Results: A total of 194 hemoglobin measurements were used. The bias and inaccuracy of these models were -2.69 and35.62 for the H group, -1.53 and 43.21 for the V group, and 9.05 and 41.82 for the X group, respectively. The bloodvolumedilution and target dilution of body-fluid space showed a significant linear relationship in each group (P < 0.05).
Conclusions: Based on the inaccuracy of predictive performance, the fluid-kinetic model for Hartmann’s solutionshowed better performance than the other models.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Arieff AI. / 1999 / Fatal postoperative pulmonary edema : pathogenesis and literature review / Chest 115:1371~1377
Cousins MJ / 1983 / Anaesthesia and the kidney / Anaesth Intensive Care 11:292~320
Chappell D / 2008 / A rational approach to perioperative fluid management / Anesthesiology 109:723~740
Zhang Z / 2011 / Accuracy of stroke volume variation in predicting fluid responsiveness : a systematic review and metaanalysis / J Anesth 25:904~916
Cannesson M / 2011 / Pulse pressure variation : where are we today? / J Clin Monit Comput 25:45~56
Cousins MJ / 1983 / Anaesthesia and the kidney / Anaesth Intensive Care 11:292~320
Chappell D / 2008 / A rational approach to perioperative fluid management / Anesthesiology 109:723~740
Zhang Z / 2011 / Accuracy of stroke volume variation in predicting fluid responsiveness : a systematic review and metaanalysis / J Anesth 25:904~916
Cannesson M / 2011 / Pulse pressure variation : where are we today? / J Clin Monit Comput 25:45~56
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