지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Latest guidelines on lipid management recommend statins as the first-line therapy. Because limited evidence is available on cardiovascular outcomes with varying statin-nonstatin combinations, recommendation levels for these regimens have been weak. However, a recent trial has demonstrated the additive effect of the statinezetimibe combination. The statin-fibrate combination has shown an effect in certain subgroups and on diabetic microangiopathy. Recent trials using the statin-niacin combination have been largely negative, whereas the statinomega- 3 fatty acids combination demonstrated a positive effect only in one study. Identifying the benefits and limitations of each combination is important for the best possible management of patients.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
European Association for Cardiovascular Prevention & Re-habilitation / 2011 / ESC Committee for Practice Guidelines (CPG) 2008-2010 and 2010-2012 Committees. ESC/EAS Guidelines for the management of dys-lipidaemias : the Task Force for the management of dyslipi-daemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) / Eur Heart J 32:1769~1818
Stone NJ / 2014 / American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults : a report of the American College of Cardiology/American Heart Asso-ciation Task Force on Practice Guidelines / Circulation 129:1~45
Cholesterol Treatment Trialists’(CTT)Collaboration / 2010 / Efficacy and safety of more intensive lowering of LDL cholesterol : a meta-analysis of data from 170,000 participants in 26 randomised trials / Lancet 376:1670~1681
ACCORD Study Group / 2010 / Effects of combination lipid therapy in type 2 diabetes mellitus / N Engl J Med 362:1563~1574
AIM-HIGH Investigators / 2011 / Niacin in patients with low HDL cho-lesterol levels receiving intensive statin therapy / N Engl J Med 365:2255~2267
Stone NJ / 2014 / American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults : a report of the American College of Cardiology/American Heart Asso-ciation Task Force on Practice Guidelines / Circulation 129:1~45
Cholesterol Treatment Trialists’(CTT)Collaboration / 2010 / Efficacy and safety of more intensive lowering of LDL cholesterol : a meta-analysis of data from 170,000 participants in 26 randomised trials / Lancet 376:1670~1681
ACCORD Study Group / 2010 / Effects of combination lipid therapy in type 2 diabetes mellitus / N Engl J Med 362:1563~1574
AIM-HIGH Investigators / 2011 / Niacin in patients with low HDL cho-lesterol levels receiving intensive statin therapy / N Engl J Med 365:2255~2267
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