지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 281 - 290 (10page)
- DOI
- 10.3393/ac.2021.03.15
이용수
초록· 키워드
오류제보하기
Purpose: Proctectomy for the treatment of rectal cancer results in inevitable changes to bowel habits. Symptoms such as fecal incontinence, constipation, and tenesmus are collectively referred to as low anterior resection syndrome (LARS). Among the several risk factors that cause LARS, anastomotic leakage (AL) is a strong risk factor for permanent stoma formation. Therefore, the purpose of this study was to investigate the relationship between the severity of LARS and AL in patients with rectal cancer based on the LARS score and the Memorial Sloan Kettering Cancer Center (MSKCC) defecation symptom questionnaires.Methods: We retrospectively analyzed patients who underwent low anterior resection for rectal cancer since January 2010. Patients who completed the questionnaire were classified into the AL group and control group based on medical and imaging records. Major LARS and MSKCC scores were analyzed as primary endpoints.Results: Among the 179 patients included in this study, 37 were classified into the AL group. After propensity score matching, there were significant differences in the ratio of major LARS and MSKCC scores of the control group and AL group (ratio of major LARS: 11.1% and 37.8%, P<0.001; MSKCC score: 67.29±10.4 and 56.49±7.2, respectively, P<0.001). Univariate and multivariate analyses revealed that AL was an independent factor for major LARS occurrence and MSKCC score.Conclusion: This study showed that AL was a significant factor in the occurrence of major LARS and defecation symptoms after proctectomy.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Allemani C / 2018 / Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries / Lancet 391:1023~1075
Bryant CL / 2012 / Anterior resection syndrome / Lancet Oncol 13:e403~e408
Sarcher T / 2018 / Anterior resection syndrome: what should we tell practitioners and patients in 2018? / J Visc Surg 155:383~391
Emmertsen KJ / 2012 / Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer / Ann Surg 255:922~928
Martellucci J / 2018 / Role of transanal irrigation in the treatment of anterior resection syndrome / Tech Coloproctol 22:519~527
Bryant CL / 2012 / Anterior resection syndrome / Lancet Oncol 13:e403~e408
Sarcher T / 2018 / Anterior resection syndrome: what should we tell practitioners and patients in 2018? / J Visc Surg 155:383~391
Emmertsen KJ / 2012 / Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer / Ann Surg 255:922~928
Martellucci J / 2018 / Role of transanal irrigation in the treatment of anterior resection syndrome / Tech Coloproctol 22:519~527
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