지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제15권 제4호
- 발행연도
- 2017.1
- 수록면
- 328 - 336 (9page)
이용수
초록· 키워드
오류제보하기
Objective: Risperidone has been widely used to control aggression and conduct disorder (CD) in youth; however, treatment compliance is a major problem in CD. Our aim is to evaluate the effectiveness and tolerability of long-acting risperidone (LAR) in treating nonadherent cases. Methods: The medical records of children and adolescents who had CD and were nonadherent to conventional drugs and psychosocial interventions (and therefore taking LAR) were reviewed. Informed consent on offlabel use of LAR was obtained from the parents. Clinical Global Impression (CGI) Severity (CGI-S) and CGI-Improvement scales were used and baseline and end points were compared. Results: The study comprised 14 children and adolescents (5 girls, 9 boys). All had comorbid disorders: substance use disorder (n=8), attention deficit hyperactivity disorder (n=6), and major depression (n=2). Mean duration of LAR use was 3.1 months (1.5-8 months). We observed significant improvements in the baseline and endpoint CGI-S scores for CD in all but one patient (Z=−3.198; p ＜0.001). Only mild adverse effects were observed: weight gain (n=2), sedation (n=1), leg cramps (n=1), and increased appetite with no weight gain (n=1). Conclusion: LAR is effective and tolerable for patients with CD who can’t be medicated with oral preparations due to nonadherence to treatment. Even short-term LAR use is effective to get compliance. As CD predicts numerous problems in adulthood, appropriate treatment is crucial. To our knowledge, this is the first study on LAR use in youth with CD. The use of LAR deserves careful consideration and further controlled studies are needed to confirm our findings.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Aman MG / 2014 / What does risperidone add to parent training and stimulant for severe aggression in
American Psychiatric Association / 2013 / Diagnostic and statistical manual of mental disorders: DSM-5 / American Psychiatric Association
Connor DF / 2008 / Randomized controlled pilot study of quetiapine in the treatment of adolescent conduct disorder / J Child Adolesc Psychopharmacol 18 : 140 ~ 156
Costello EJ / 2003 / Prevalence and development of psychiatric disorders in childhood and adolescence / Arch Gen Psychiatry 60 : 837 ~ 844
Crystal S / 2009 / Broadened use of atypical antipsychotics: safety, effectiveness, and policy challenges / Health Aff (Millwood) 28 : w770 ~ w781
American Psychiatric Association / 2013 / Diagnostic and statistical manual of mental disorders: DSM-5 / American Psychiatric Association
Connor DF / 2008 / Randomized controlled pilot study of quetiapine in the treatment of adolescent conduct disorder / J Child Adolesc Psychopharmacol 18 : 140 ~ 156
Costello EJ / 2003 / Prevalence and development of psychiatric disorders in childhood and adolescence / Arch Gen Psychiatry 60 : 837 ~ 844
Crystal S / 2009 / Broadened use of atypical antipsychotics: safety, effectiveness, and policy challenges / Health Aff (Millwood) 28 : w770 ~ w781
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Validation of Korean Version of Low Anterior Resection Syndrome Score Questionnaire
Annals of Coloproctology
2020 .01
-
Postoperative Bowel Function After Anal Sphincter-Preserving Rectal Cancer Surgery: Risks Factors, Diagnostic Modalities, and Management
Annals of Coloproctology
2019 .01
-
The Effect of Anastomotic Leakage on the Incidence and Severity of Low Anterior Resection Syndrome in Patients Undergoing Proctectomy: A Propensity Score Matching Analysis
대한외과학회 학술대회 초록집
2021 .05
-
Robotic Versus Laparoscopic Surgery for Rectal Cancer after Preoperative Chemoradiotherapy: Case-Matched Study of Short-Term Outcomes
Cancer Research and Treatment
2016 .01
-
The Effect of Anastomotic Leakage on the Incidence and Severity of Low Anterior Resection Syndrome in Patients Undergoing Proctectomy: A Propensity Score Matching Analysis
Annals of Coloproctology
2021 .10
-
Efficacy of biofeedback therapy for objective improvement of pelvic function in low anterior resection syndrome
Annals of Surgical Treatment and Research
2019 .10
-
Efficacy of Revisional Antireflux Surgery for Failed Endoscopic Antireflux Therapy
대한외과학회 학술대회 초록집
2021 .05
-
Laparoscopic Reinforcement Suture (LARS) on Staple Line of Duodenal Stump Using Barbed Suture in Laparoscopic Gastrectomy for Gastric Cancer: a Prospective Single Arm Phase II Study
Journal of Gastric Cancer
2017 .12
-
The impact of early and late acute rejection on graft survival in renal transplantation
Kidney Research and Clinical Practice
2015 .01
-
국소 알레르기비염의 최신지견
대한이비인후-두경부외과학회지
2021 .08
-
Usefulness of Anorectal Manometry for Diagnosing Continence Problems After a Low Anterior Resection
Annals of Coloproctology
2016 .01
-
Laboratory Animal Research (LAR) to be published by BioMed Central from 2019!
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Development and Effectiveness of Bowel Function Improvement Program for Postoperative Male Rectal Cancer Patients
성인간호학회 학술대회
2021 .08
-
The effect of laparoscopic versus robotic low anterior resection of rectum on postoperative pain : A propensity score matching analysis
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2016 .12
-
Risperidone Monotherapy in Children and Adolescents with Autism Spectrum Disorders : A Naturalistic Study
소아청소년정신의학
2015 .12
-
Efficacy and Safety Profile of Risperidone Long-acting Injection in Adolescents in a Real-life Setting
Clinical Psychopharmacology and Neuroscience
2018 .01
-
Extrinsic Acquisition of CD80 by Antigen-Specific CD8⁺ T Cells Regulates Their Recall Immune Responses to Acute Viral Infection
Immune Network
2019 .08
-
중증 외상 환자에서의The prognostic usefulness of the lactate/albumin ratio for predicting multiple organ dysfunction syndrome in severe trauma 다발성 장기부전 발생 예측에 있어 젖산/알부민값의 유용성
대한응급의학회지
2022 .02
-
Leukemia propagating cells in Philadelphia chromosome-positive ALL: a resistant phenotype with an adverse prognosis
Blood Research
2018 .01
-
Two Distinct Subsets Are Identified from the Peritoneal Myeloid Mononuclear Cells Expressing both CD11c and CD115
Immune Network
2019 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0