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논문 기본 정보

자료유형
학술저널
저자정보
Zhu Yuanyue (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Wang Long (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Lin Lin (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Huo Yanan (Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, China) Wan Qin (The Affiliated Hospital of Luzhou Medical College, Luzhou, China) Qin Yingfen (The First Affiliated Hospital of Guangxi Medical University, Nanning, China) Hu Ruying (Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China) Shi Lixin (Affiliated Hospital of Guiyang Medical University, Guiyang, China) Su Qing (Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China) Yu Xuefeng (Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China) Yan Li (Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China) Qin Guijun (The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China) Tang Xulei (The First Hospital of Lanzhou University, Lanzhou, China) Chen Gang (Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China) Wang Shuangyuan (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Lin Hong (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Wu Xueyan (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Hu Chunyan (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Li Mian (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Xu Min (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Xu Yu (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Wang Tiange (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Zhao Zhiyun (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Gao Zhengnan (Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China) Wang Guixia (The First Hospital of Jilin University, Changchun, China) Shen Feixia (The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China) Gu Xuejiang (The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China) Luo Zuojie (The First Affiliated Hospital of Guangxi Medical University, Nanning, China) Chen Li (Qilu Hospital of Shandong University, Jinan, China) Li Qiang (The Second Affiliated Hospital of Harbin Medical University, Harbin, China) Ye Zhen (Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China) Zhang Yinfei (Central Hospital of Shanghai Jiading District, Shanghai, China) Liu Chao (Jiangsu Province Hospital on Integration of Chinese and Western Medicine, Nanjing, China) Wang Youmin (The First Affiliated Hospital of Anhui Medical University, Hefei, China) Wu Shengli (Karamay Municipal People’s Hospital, Xinjiang, China) Yang Tao (The First Affiliated Hospital of Nanjing Medical University, Nanjing, China) Deng Huacong (The First Affiliated Hospital of Chongqing Medical University, Chongqing, China) Chen Lulu (Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China) Zeng Tianshu (Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China) Zhao Jiajun (Shandong Provincial Hospital affiliated to Shandong University, Jinan, China) Mu Yiming (Chinese People’s Liberation Army General Hospital, Beijing, China) Wang Weiqing (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Ning Guang (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Bi Yufang (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Chen Yuhong (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan) Lu Jieli (Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShan)
저널정보
거트앤리버 발행위원회 Gut and Liver Gut and Liver Vol.18 No.4
발행연도
2024.7
수록면
719 - 728 (10page)
DOI
10.5009/gnl230220

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Background/Aims: Low educational attainment is a well-established risk factor for nonalcoholic fatty liver disease (NAFLD) in developed areas. However, the association between educational attainment and the risk of NAFLD is less clear in China. Methods: A cross-sectional study including over 200,000 Chinese adults across mainland China was conducted. Information on education level and lifestyle factors were obtained through standard questionnaires, while NAFLD and advanced fibrosis were diagnosed using validated formulas. Outcomes included the risk of NAFLD in the general population and high probability of fibrosis among patients with NAFLD. Logistic regression analysis was employed to estimate the risk of NAFLD and fibrosis across education levels. A causal mediation model was used to explore the potential mediators. Results: Comparing with those receiving primary school education, the multi-adjusted odds ratios (95% confidence intervals) for NAFLD were 1.28 (1.16 to 1.41) for men and 0.94 (0.89 to 0.99) for women with college education after accounting for body mass index. When considering waist circumference, the odds ratios (95% CIs) were 0.94 (0.86 to 1.04) for men and 0.88 (0.80 to 0.97) for women, respectively. The proportions mediated by general and central obesity were 51.00% and 68.04% for men, while for women the proportions were 48.58% and 32.58%, respectively. Furthermore, NAFLD patients with lower educational attainment showed an incremental increased risk of advanced fibrosis in both genders. Conclusions: In China, a low education level was associated with a higher risk of prevalent NAFLD in women, as well as high probability of fibrosis in both genders.

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