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논문 기본 정보

자료유형
학술저널
저자정보
Ki Young Jun (Department of Anesthesiology and Pain Medicine, Jeollanam-do Gangjin Medical Center, Gangjin, Korea) Kim Sang Hun (Department of Anesthesiology and Pain Medicine, School of Medicine, Chosun University, Gwangju, KoreaDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Kore) So Keum Young (Department of Anesthesiology and Pain Medicine, School of Medicine, Chosun University, Gwangju, KoreaDepartment of Anesthesiology and Pain Medicine, Chosun University Hospital, Gwangju, Kore)
저널정보
조선대학교 의학연구원 Medical Biological Science and Engineering Medical Bilogical Science and Engineering Vol.7 No.2
발행연도
2024.7
수록면
84 - 90 (7page)
DOI
10.30579/mbse.2024.7.2.84

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Opioid use in total intravenous anesthesia (TIVA) poses a risk of postoperative respiratory de pression due to the residual effects of opioids. Naloxone, an opioid antagonist, can improve anesthesia recovery by stimulating respiratory ventilation and reversing opioid effects. Therefore, this retrospective review of electronic medical records aimed to evaluate the effect of naloxone on anesthesia recovery after TIVA. A total of 304 patients aged 20-100 years with an Ameri can Society of Anesthesiologists physical status of I-III were assigned to two groups. Group N (naloxone; n=178) received naloxone at the end of surgery, while Group C (control; n=126) did not. After propensity score matching (PSM), 252 patients were allocated to Group C (n=126) or Group N (n=126). The discharge time from the operating room (Dis_OR) and recovery room (RR), Modified Aldrete Score at RR admission and discharge, and incidence of sedation and agitation in the RR were investigated. Before the PSM analysis, the mean Dis_OR was shorter in Group N (11.1 min; 95% confidence interval [CI], 10.4-11.7 min) than in Group C (19.4 min; 95% CI, 18.8-20.0 min) (p<0.001). After the PSM analysis, the mean Dis_OR was shorter in Group N (11.2 min; 95% CI, 10.4-12.0 min) than in Group C (19.4 min; 95% CI, 18.8-20.0 min) (p<0.001). No significant intergroup differences in other parameters were noted before versus after PSM. Nal oxone was effective to improve anesthesia recovery after TIVA.

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