메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색
질문

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색
질문

초록· 키워드

오류제보하기
The purpose of this study was to confirm the combinational effect of red ginseng powder (RGP) and silk peptide (SP) on hypercholesterolemia and atherosclerosis in rabbits. Male New Zealand White rabbits were fed only high-cholesterol diet (HCD) containing 0.5% cholesterol and 1% corn oil for 2 weeks, and then RGP (3%), SP (1% or 3%) or their combinations were added to a diet containing 0.25% cholesterol and 1% corn oil for additional 8 weeks. Blood total cholesterol and low-density lipoproteins (LDL) were greatly increased by 2-week feeding HCD to 13-15 folds of control, in contrast to the reduction of highdensity lipoproteins (HDL) to a half level. Additional 8-week feeding HCD caused thick atheromatous plaques, covering 65.8-67.3% of the aortic wall, and hepatocytic lipid peroxidation, leading to vacuolar and fatty degeneration. Such a hypercholesterolemia was significantly reduced by addition of RGP, in comparison with a mild effect of SP. In addition, HCD-induced decrease in HDL and increase in triglycerides were reversed by RGP and SP. Moreover, the atheroma area on the aortic wall as well as hepatocytic lipid peroxidation and degeneration were markedly attenuated by RGP. Especially, the effects of RGP on blood lipid profiles, atheroma formation and hepatocytic damage were potentiated by the combination of SP. The results suggest that RGP improves hypercholestarolemia and ensuing atherosclerosis, probably by both controlling lipid metabolism and reducing free radical reactions, which is synergistically enhanced by SP.

목차

재료 및 방법
결과
고찰
감사의 글
참고문헌

참고문헌 (31)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

이 논문과 함께 이용한 논문

최근 본 자료

전체보기

댓글(0)

0

UCI(KEPA) : I410-ECN-0101-2009-510-014753564