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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.14 No.1
- 발행연도
- 2009.3
- 수록면
- 37 - 42 (6page)
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초록· 키워드
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The protective activity of seolitae chungkukjang added with green tea against oxidative stress was investigated under the cellular systems using LLC-PK1 cells. The treatment of 2,2'-azobis(2-aminopropane) dihydrochloride (AAPH) showed increase in lipid peroxidation, and decrease in endogenous antioxidant enzymes activity and cell viability. However, the methanol extract of seolitae chungkukjang inhibited lipid peroxidation by 58.3%, and increased cell viability up to more than 60%. In addition, it enhanced superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities. Seolitae chungkukjang improved oxidative stress-induced cellular injury through the radical scavenging activities. In particular, the addition of green tea in seolitae chungkukjang showed stronger effect against oxidative stress induced by AAPH. The more addition of green tea resulted in the greater antioxidative effect through elevation in activities of SOD and GSH-Px, and inhibition of lipid peroxidation, eventually leading to increase in cell viability. Theses results suggested that seolitae chungkukjang added with green tea have protective effects from cellular oxidative damage and could be considered as an application for the development of chungkukjang with functionality.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (27)
참고문헌 신청
1. [학술지(정기간행물)] - Dooley MM / 1990 / Effects of 2,2′-azobis 2-amidinopropane hydrochloride in vivo and protection by vitamin E / Free Radic Biol Med : 199 ~ 204
2. [학술지(정기간행물)] - Noguchi N / 1998 / 2,2′-Azobis (4-methoxy-2,4-dimethylvaleronitrile), a new lipid-soluble azo initiator: application to oxidations of lipids and low-density lipoprotein in solution and in aqueous dispersions / Free Radic Biol Med : 259 ~ 268
3. [학술지(정기간행물)] - Terao K / 1986 / Damage to biological tissues induced by radical initiator 2,2′-azobis (2-amidinopropane) dihydrochloride and its inhibition by chain-breaking antioxidants / Free Radic Biol Med : 193 ~ 201
4. [학술지(정기간행물)] - Miki M / 1987 / Free-radical chain oxidation of rat red blood cells by molecular oxygen and its inhibition by tocopherol / Arch Biochem Biophys : 373 ~ 380
5. [학술지(정기간행물)] - Yokozawa T / 2000 / Antioxidative activity of green tea treated with radical initiator 2,2′-azobis(2-aminopropane)dihydrochloride / J Agric Food Chem : 5068 ~ 5073
2. [학술지(정기간행물)] - Noguchi N / 1998 / 2,2′-Azobis (4-methoxy-2,4-dimethylvaleronitrile), a new lipid-soluble azo initiator: application to oxidations of lipids and low-density lipoprotein in solution and in aqueous dispersions / Free Radic Biol Med : 259 ~ 268
3. [학술지(정기간행물)] - Terao K / 1986 / Damage to biological tissues induced by radical initiator 2,2′-azobis (2-amidinopropane) dihydrochloride and its inhibition by chain-breaking antioxidants / Free Radic Biol Med : 193 ~ 201
4. [학술지(정기간행물)] - Miki M / 1987 / Free-radical chain oxidation of rat red blood cells by molecular oxygen and its inhibition by tocopherol / Arch Biochem Biophys : 373 ~ 380
5. [학술지(정기간행물)] - Yokozawa T / 2000 / Antioxidative activity of green tea treated with radical initiator 2,2′-azobis(2-aminopropane)dihydrochloride / J Agric Food Chem : 5068 ~ 5073
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