지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.8
- 수록면
- 375 - 384 (10page)
이용수
초록· 키워드
오류제보하기
Trichomonas vaginalis is a pathogen that triggers severe immune responses in hosts. T. vaginalis α-actinin 2, Tvα-actinin 2, has been used to diagnose trichomoniasis. This study was undertaken to examine the role of Tvα-actinin 2 as an antigenic molecule to induce immune responses from humans. Western blot analysis using anti-Tvα-actinin 2 antibodies indicated its presence in the secreted proteins of T. vaginalis. ELISA was employed to measure cytokine production by vaginal epithelial cells, prostate cells, mouse dendritic cells (DCs), or T cells stimulated with T. vaginalis or Tvα- actinin 2 protein. Both T. vaginalis and rTvα-actinin 2 induced cytokine production from epithelial cell lines, including IL- 10. Moreover, CD4+CD25- regulatory T cells (Treg cells) incubated with rTvα-actinin 2-treated DCs produced high levels of IL-10. These data indicate that Tvα-actinin 2 modulates immune responses via IL-10 production by Treg cells.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGMENT
REFERENCES
참고문헌 (28)
참고문헌 신청
[학술지(정기간행물)] - Fouts AC / 1993 / Trichomonas vaginalis : reevaluation of its clinical presentation and laboratory diagnosis / J Infect Dis 141 : 137 ~ 143
[학술지(정기간행물)] - Fiori PL / 1999 / The flagellated parasite Trichomonas vaginalis : new insights into cytopathogenicity mechanisms / Microbes Infect 1 : 149 ~ 156
[학술지(정기간행물)] - Figueroa-Angulo EE / 2012 / The effects of environmental factors on the virulence of Trichomonas vaginalis / Microbes Infect 14 : 1411 ~ 1427
[학술지(정기간행물)] - Hye-Yeon Lee / 2011 / Identification of Antigenic Proteins in Trichomonas vaginalis / The Korean Journal of Parasitology 49 (1) : 79 ~ 83
[학술지(정기간행물)] - Dixson JD / 2003 / The α-actinin gene family : a revised classification / J Mol Evol 56 : 1 ~ 10
[학술지(정기간행물)] - Fiori PL / 1999 / The flagellated parasite Trichomonas vaginalis : new insights into cytopathogenicity mechanisms / Microbes Infect 1 : 149 ~ 156
[학술지(정기간행물)] - Figueroa-Angulo EE / 2012 / The effects of environmental factors on the virulence of Trichomonas vaginalis / Microbes Infect 14 : 1411 ~ 1427
[학술지(정기간행물)] - Hye-Yeon Lee / 2011 / Identification of Antigenic Proteins in Trichomonas vaginalis / The Korean Journal of Parasitology 49 (1) : 79 ~ 83
[학술지(정기간행물)] - Dixson JD / 2003 / The α-actinin gene family : a revised classification / J Mol Evol 56 : 1 ~ 10
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Interaction between Trichomonas vaginalis and the Prostate Epithelium
Parasites, Hosts and Diseases
2017 .04
-
Inflammatory response to Trichomonas vaginalis in the pathogenesis of prostatitis and benign prostatic hyperplasia
Parasites, Hosts and Diseases
2023 .02
-
Proliferation of Mouse Prostate Cancer Cells Inflamed by Trichomonas vaginalis
Parasites, Hosts and Diseases
2021 .12
-
Influence of 120 kDa Pyruvate:Ferredoxin Oxidoreductase on Pathogenicity of Trichomonas vaginalis
Parasites, Hosts and Diseases
2016 .02
-
Prevalence of Trichomoniasis by PCR in Women Attending Health Screening in Korea
Parasites, Hosts and Diseases
2016 .04
-
Loop-Mediated Isothermal Amplification Targeting Actin DNA of Trichomonas vaginalis
Parasites, Hosts and Diseases
2016 .06
-
Prevalence of Trichomonas vaginalis in Women Visiting 2 Obstetrics and Gynecology Clinics in Daegu, South Korea
Parasites, Hosts and Diseases
2016 .02
-
Inflammatory Responses in a Benign Prostatic Hyperplasia Epithelial Cell Line (BPH-1) Infected with Trichomonas vaginalis
Parasites, Hosts and Diseases
2016 .04
-
Differential Protein Expressions in Virus-Infected and Uninfected Trichomonas vaginalis
Parasites, Hosts and Diseases
2017 .04
-
Immune Response of BALB/c Mice toward Putative Calcium Transporter Recombinant Protein of Trichomonas vaginalis
Parasites, Hosts and Diseases
2019 .02
-
Signaling Role of Adipocyte Leptin in Prostate Cell Proliferation Induced by Trichomonas vaginalis
Parasites, Hosts and Diseases
2021 .06
-
Involvement of Macrophages in Proliferation of Prostate Cancer Cells Infected with Trichomonas vaginalis
Parasites, Hosts and Diseases
2021 .12
-
CysLT receptor-mediated NOX2 activation is required for IL-8 production in HMC-1 cells induced by Trichomonas vaginalis-derived secretory products
Parasites, Hosts and Diseases
2024 .08
-
Comparison of Seropositivity to Trichomonas vaginalis between Men with Prostatic Tumor and Normal Men
Parasites, Hosts and Diseases
2019 .02
-
Excretory-Secretory Products of Trichomonas vaginalis Cause Apoptosis in Mouse Sperm in Vitro
Parasites, Hosts and Diseases
2022 .10
-
Out-sourcing for Trans-presentation : Assessing T Cell Intrinsic and Extrinsic IL-15 Expression with Il15 Gene Reporter Mice
Immune Network
2018 .02
-
Involvement of PI3K/AKT and MAPK Pathways for TNF-α Production in SiHa Cervical Mucosal Epithelial Cells Infected with Trichomonas vaginalis
Parasites, Hosts and Diseases
2015 .08
-
Regulation of Th2 Cell Immunity by Dendritic Cells
Immune Network
2016 .02
-
Tumor-derived CD4+CD25+ Tregs Inhibit the Maturation and Antigen-Presenting Function of Dendritic Cells
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Comparison of Two PCR Assays for Trichomonas vaginalis
Parasites, Hosts and Diseases
2019 .02
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2018-513-001258716