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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.23 No.1
- 발행연도
- 2018.3
- 수록면
- 8 - 14 (7page)
- DOI
- 10.3746/pnf.2018.23.1.8
이용수
초록· 키워드
오류제보하기
The cholesterol-lowering and anti-atherogenic effects of lemon essential oil (LEO) were investigated and compared with the effects of limonene. Owing to their volatility, both LEO and limonene were microencapsulated before preparation of the diet (20%, w/w). Hypercholesterolemia-induced rabbits were divided into 3 groups based on plasma total cholesterol (TC) levels and fed coating matrix (control group), LEO (LEO group), or limonene (Limonene group) for 8 weeks. LEO dose-dependently inhibited low-density lipoprotein oxidation in vitro. Plasma TC levels were the lowest in the LEO group (P<0.05). Erythrocytes in the LEO group had a normal disc shape, whereas the erythrocytes in the limonene and control groups were aggregated and star-shaped, respectively. The aortic intima thickness was thinnest in the LEO group followed by the control and limonene groups. Plasma TC lowering and anti-atherogenic effects of LEO were greater than limonene, suggesting that other bioactive compounds besides limonene in LEO might contribute to these effects. The bioactive compounds in LEO were limonene (67.57%), β-pinene (10.00%), and γ-terpinene (9.95%). In addition, sabinene, α-pinene, myrcene, and geranial were also present but the amount was in the range of 1∼2%. Several bioactive compounds were also detected. In conclusion, LEO had beneficial effects on hypercholesterolemia due to its antioxidative and cholesterol lowering effects.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (35)
참고문헌 신청
[학술지(정기간행물)] - Solorzano-Santos F / 2012 / Essential oils from aromatic herbs as antimicrobial agents / Curr Opin Biotechnol 23 : 136 ~ 141
[학술지(정기간행물)] - Misharina TA / 2008 / Antioxidant properties of essential oils from lemon, grapefruit, coriander, clove, and their mixtures / Prikl Biokhim Mikrobiol 44 : 438 ~ 442
[학술지(정기간행물)] - Sharififar F / 2011 / In vivo antioxidant activity of Zataria multiflora Boiss essential oil / Pak J Pharm Sci 24 : 221 ~ 225
[학술지(정기간행물)] - Monteiro MVB / 2007 / Topical anti-inflammatory, gastroprotective and antioxidant effects of the essential oil of Lippia sidoides Cham. leaves / J Ethnopharmacol 111 : 378 ~ 382
[학술지(정기간행물)] - Hyo Jung Kim / 2011 / Antiobesity Effect of Oil Extract of Ginseng / Journal of Medicinal Food 14 (6) : 573 ~ 583
[학술지(정기간행물)] - Misharina TA / 2008 / Antioxidant properties of essential oils from lemon, grapefruit, coriander, clove, and their mixtures / Prikl Biokhim Mikrobiol 44 : 438 ~ 442
[학술지(정기간행물)] - Sharififar F / 2011 / In vivo antioxidant activity of Zataria multiflora Boiss essential oil / Pak J Pharm Sci 24 : 221 ~ 225
[학술지(정기간행물)] - Monteiro MVB / 2007 / Topical anti-inflammatory, gastroprotective and antioxidant effects of the essential oil of Lippia sidoides Cham. leaves / J Ethnopharmacol 111 : 378 ~ 382
[학술지(정기간행물)] - Hyo Jung Kim / 2011 / Antiobesity Effect of Oil Extract of Ginseng / Journal of Medicinal Food 14 (6) : 573 ~ 583
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UCI(KEPA) : I410-ECN-0101-2018-594-001907113