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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.3
- 수록면
- 308 - 311 (4page)
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초록· 키워드
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Extracts of ginseng species show antihyperglycemic activity. We evaluated the inhibitory effects of diabetic complications for Korean Red Ginseng (KRG), which is enriched in ginsenosides using Otsuka Long-Evans Tokushima Fatty (OLETF) rats. The animals were divided into one of four groups (n = 6~9): Long-Evans-Tokushima-Otsuka rats (control rats), OLETF rats, rats given 200 mg/kg KRG, and rats given 400 mg/kg KRG. We examined the protective potential of KRG against type 2 diabetic illnesses. The results exhibited that KRG showed significant antihyperglycemic and antioxidative effects in KRG-treated OLETF rats. And, our results proposed the amelioration of cardiac function through normalized ejection fraction, fractional shortening, and vascular reactivity. Furthermore, histopathological abnormalities in the OLETF rats were prevented by KRG treatment.
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참고문헌 (9)
참고문헌 신청
Wild S / 2004 / Global prevalence of diabetes : estimates for the year 2000 and projections for 2030 / Diabetes Care 27(5):1047~1053
Sung J / 2000 / Effects of red ginseng upon vascular endothelial function in patients with essential hypertension / Am J Chin Med 28(2):205~216
Jung CH / 2005 / Effects of wild ginseng(panax ginseng C. A. Meyer)leaves on lipid peroxidation levels and antioxidant enzyme activities in streptozotocin diabetic rats / J Ethnopharmacol 98:245~250
Li HX / 2012 / The saponin of red ginseng protects the cardiac myocytes against ischemic injury in vitro and in vivo / Phytomedicine 19(6):477~483
Yang C / 2013 / Protective effect of curcumin against cardiac dysfunction in sepsis rats / Pharm Biol 51(4):482~487
Sung J / 2000 / Effects of red ginseng upon vascular endothelial function in patients with essential hypertension / Am J Chin Med 28(2):205~216
Jung CH / 2005 / Effects of wild ginseng(panax ginseng C. A. Meyer)leaves on lipid peroxidation levels and antioxidant enzyme activities in streptozotocin diabetic rats / J Ethnopharmacol 98:245~250
Li HX / 2012 / The saponin of red ginseng protects the cardiac myocytes against ischemic injury in vitro and in vivo / Phytomedicine 19(6):477~483
Yang C / 2013 / Protective effect of curcumin against cardiac dysfunction in sepsis rats / Pharm Biol 51(4):482~487
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UCI(KEPA) : I410-ECN-0101-2020-524-000504384