지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 573 - 580 (8page)
이용수
초록· 키워드
오류제보하기
Background and Purpose Recent quantitative neuroimaging studies of childhood absence epilepsy (CAE) have identified various structural abnormalities that might be involved in the onset of absence seizure and associated cognitive and behavioral functions. However, the neuroanatomical alterations specific to CAE remain unclear, and so this study investigated the regional alterations of brain structures associated with newly diagnosed CAE. Methods Surface and volumetric magnetic resonance imaging data of patients with newly diagnosed CAE (n=18) and age-matched healthy controls (n=18) were analyzed using Free- Surfer software. A group comparison using analysis of covariance was performed with significance criteria of p<0.05 and p<0.01 in global and regional analyses, respectively. Results Compared with control subjects, the patients with CAE had smaller total and regional volumes of cortical gray-matter (GM) in the right rostral middle frontal, right lateral orbitofrontal, and left rostral middle frontal regions, as well as in the right precentral, right superior, middle, left middle, and inferior temporal gyri. The cortex in the right posterior cingulate gyrus and left medial occipital region was significantly thicker in patients with CAE than in controls. Conclusions Patients with CAE showed a reduced bilateral frontotemporal cortical GM volume and an increased posterior medial cortical thickness, which are associated with the default mode network. These structural changes can be suggested as the neural basis of the absence seizures and neuropsychiatric comorbidities in CAE.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Cerebral Air Embolism: a Case Report with an Emphasis of its Pathophysiology and MRI Findings
Investigative Magnetic Resonance Imaging
2019 .01
-
Effects of Moderate Intensity Exercise on the Cortical Thickness and Subcortical Volumes of Preclinical Alzheimer’s Disease Patients: A Pilot Study
PSYCHIATRY INVESTIGATION
2020 .01
-
Regional Brain Volume Changes in Catholic Nuns: A Cross-Sectional Study Using Deep Learning-Based Brain MRI Segmentation
PSYCHIATRY INVESTIGATION
2022 .09
-
Analysis of Altered Baseline Brain Activity in Drug-Naive Adult Patients with Social Anxiety Disorder Using Resting-State Functional MRI
PSYCHIATRY INVESTIGATION
2015 .01
-
Childhood Sexual Abuse and Cortical Thinning in Adults With Major Depressive Disorder
PSYCHIATRY INVESTIGATION
2023 .04
-
Comparison of mean platelet volume levels in coronary artery ectasia and healthy people: systematic review and meta-analysis
Blood Research
2018 .01
-
Cerebral Cortex Changes in Basketball Players
Journal of Korean Medical Science
2022 .03
-
특발정상압수두증 환자의 보행 패턴과 대뇌피질의 구조적인 특징의 상관관계 분석
의공학회지
2021 .12
-
Alterations in the Occipital Cortex of Drug-Naive Adults With Major Depressive Disorder: A Surface-Based Analysis of Surface Area and Cortical Thickness
PSYCHIATRY INVESTIGATION
2021 .10
-
Cortical Thickness and White Matter Hyperintensity Changes Are Associated With Sarcopenia in the Cognitively Normal Older Adults
PSYCHIATRY INVESTIGATION
2022 .08
-
Alteration of Semantic Networks during Swear Words Processing in Schizophrenia
Clinical Psychopharmacology and Neuroscience
2019 .01
-
Topological Alterations of the Intrinsic Brain Network in Patients with Functional Dyspepsia
Journal of Neurogastroenterology and Motility (JNM)
2016 .01
-
Cortical Morphometric Abnormality and Its Association with Working Memory in Children with Attention-Deficit/Hyperactivity Disorder
PSYCHIATRY INVESTIGATION
2021 .01
-
Regional Gray Matter Volume Reduction Associated with Major Depressive Disorder: A Voxel-Based Morphometry
Investigative Magnetic Resonance Imaging
2015 .01
-
Gray Matter Volume Reductions Were Associated with TPH1 Polymorphisms in Depressive Disorder Patients with Suicidal Attempts
PSYCHIATRY INVESTIGATION
2018 .01
-
Cortical Thickness and Brain Glucose Metabolism in Healthy Aging
Journal of Clinical Neurology
2023 .03
-
Decreased Cortical Thickness and Local Gyrification in Individuals with Subjective Cognitive Impairment
Clinical Psychopharmacology and Neuroscience
2021 .11
-
Different Cortical Thinning Patterns Depending on Their Prognosis in Individuals with Subjective Cognitive Decline
Dementia and Neurocognitive Disorders(대한치매학회지)
2019 .01
-
뇌혈관질환이 없는 노년기 우울증 환자에서 피질 두께의 감소
노인정신의학
2015 .01
-
Gray Matter Microstructural Abnormalities and Working Memory Deficits in Individuals with Schizophrenia
PSYCHIATRY INVESTIGATION
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0