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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 1,115 - 1,122 (8page)
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초록· 키워드
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The main cause of acute myocardial infarction is plaque rupture accompanied by superimposed coronary thrombosis. Thin-cap fibroatheromas (TCFAs) have been suggested as a type of lesion with a vulnerability that can cause plaque rupture. However, not only the existence of a TCFA but also the fine and complex interactions of other anatomical and hemodynamic factors, such as microcalcification in the fibrous cap, cholesterol crystal-induced inflammasome activation, the apoptosis of intraplaque macrophages, and endothelial shear stress distribution should precede a clinical event caused by plaque rupture. Recent studies are being conducted to identify these mechanisms through molecular imaging and hemodynamic assessment using computational fluid dynamics, which will result in better clinical results through selective coronary interventions.
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등록된 정보가 없습니다.
참고문헌 (45)
참고문헌 신청
Schuurman AS / 2018 / Prognostic value of intravascular ultrasound in patients with coronary artery disease / J Am Coll Cardiol 72:2003~2011
Nicholls SJ / 2018 / Effect of evolocumab on coronary plaque composition / J Am Coll Cardiol 72:2012~2021
Arbab-Zadeh A / 2015 / The myth of the"vulnerable plaque" : transitioning from a focus on individual lesions to atherosclerotic disease burden for coronary artery disease risk assessment / J Am Coll Cardiol 65:846~855
Tian J / 2014 / Distinct morphological features of ruptured culprit plaque for acute coronary events compared to those with silent rupture and thin-cap fibroatheroma : a combined optical coherence tomography and intravascular ultrasound study / J Am Coll Cardiol 63:2209~2216
Toutouzas K / 2011 / New insights by optical coherence tomography into the differences and similarities of culprit ruptured plaque morphology in non-ST-elevation myocardial infarction and ST-elevation myocardial infarction / Am Heart J 161:1192~1199
Nicholls SJ / 2018 / Effect of evolocumab on coronary plaque composition / J Am Coll Cardiol 72:2012~2021
Arbab-Zadeh A / 2015 / The myth of the"vulnerable plaque" : transitioning from a focus on individual lesions to atherosclerotic disease burden for coronary artery disease risk assessment / J Am Coll Cardiol 65:846~855
Tian J / 2014 / Distinct morphological features of ruptured culprit plaque for acute coronary events compared to those with silent rupture and thin-cap fibroatheroma : a combined optical coherence tomography and intravascular ultrasound study / J Am Coll Cardiol 63:2209~2216
Toutouzas K / 2011 / New insights by optical coherence tomography into the differences and similarities of culprit ruptured plaque morphology in non-ST-elevation myocardial infarction and ST-elevation myocardial infarction / Am Heart J 161:1192~1199
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