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논문 기본 정보

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학술저널
저자정보
Geffner Mitchell E. (The Saban Research Institute, Children’s Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA) Ranke Michael B. (Department of Pediatric Endocrinology, University Children´s Hospital, Tübingen, Germany) Wajnrajch Michael P. (Pfizer Inc., New York, NY, USA New York University Grossman School of Medicine, New York, NY, USA)
저널정보
대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatric Endocrinology & Metabolism Vol.29 No.1
발행연도
2024.2
수록면
3 - 11 (9page)
DOI
10.6065/apem.2346206.103

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The Kabi International Growth Study (KIGS) was first established in 1987 and is the largest pharmaco-epidemiological study of recombinant human growth hormone (rhGH). KIGS is aimed at evaluating long-term safety and treatment outcomes in pediatric subjects who received Genotropin rhGH therapy (Pfizer, New York, NY, USA) as prescribed by physicians in real-world clinical practice settings. KIGS data have been used to answer multiple research questions related to growth, growth prediction, and growth hormone treatment, leading to the publication of 129 peer-reviewed manuscripts and 24 biannual reports, outcomes from 10 expert meetings, and 3 books. The KIGS has shown that rhGH is safe and increases both the short-term height gain and adult height in patients with GH deficiency (GHD) and multiple other non-GHD conditions associated with short stature.

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