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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 187 - 195 (9page)
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This study was performed to investigate the antioxidant and antidiabetic activities of soybean fermented with Monascus. Also, the changes in the content of isoflavones and Monacolin K were analyzed. It was observed that the glycoside forms of daidzin and genistin were converted to aglycones of daidzein and genistein within 6 days of fermentation. The product can be used as a health functional material that can increase bioavailability. Monacolin K production was found to increase significantly with the progression of fermentation with an increase to 0.04 mg/g and 0.44 mg/g on 6 and 12 days of fermentation, respectively. The DPPH radical scavenging activity of soybean fermented with Monascus was significantly increased compared to that of soybean. The protein expression of inflammation-related genes (TNF-α, IL-6, and COX-2) in the MIN cell was significantly increased in the presence of alloxan compared to the normal group, but a decrease was observed in the presence of soybean fermented with Monascus. In conclusion, soybean fermented with Monascus showed the highest antidiabetic and antioxidant effects. These results suggest that soybean fermented with Monascus has the potential to be used as a beneficial ingredient with antidiabetic and antioxidant effects.
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참고문헌 (39)
참고문헌 신청
Bradford MM / 1976 / A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding / Anal Biochem 72:248~254
Carmichael J / 1987 / Evaluation of tetrazolium-based semiautomated colorimetric assay : Assessment of chemosensitivity testing / Cancer Res 47:936~942
Chang JC / 2005 / Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats / Horm Metab Res 37:610~616
Chen JC / 2015 / Effect of Monascus aged vinegar on isoflavone convertsion in soy germ by soaking treatment / Food Chem 186:256~264
Feghali CA / 1997 / Cytokines in acute and chronic inflammation / Front Biosci 2:12~26
Carmichael J / 1987 / Evaluation of tetrazolium-based semiautomated colorimetric assay : Assessment of chemosensitivity testing / Cancer Res 47:936~942
Chang JC / 2005 / Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats / Horm Metab Res 37:610~616
Chen JC / 2015 / Effect of Monascus aged vinegar on isoflavone convertsion in soy germ by soaking treatment / Food Chem 186:256~264
Feghali CA / 1997 / Cytokines in acute and chronic inflammation / Front Biosci 2:12~26
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