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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충남대학교 농업과학연구소 Korean Journal of Agricultural Science Korean Journal of Agricultural Science Vol.48 No.3
- 발행연도
- 2021.9
- 수록면
- 575 - 587 (13page)
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초록· 키워드
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This study was carried out to investigate the effects of supplementation with a Bifidobacteria enhanced yogurt (BE0623 yogurt), which includes Bifidobacterium lactis BB12, Lactobacillus acidophilus, Streptococcus thermophilus, and Bifidobacterium lactis, in the management of irritable bowel syndrome (IBS) using animal models and clinical trials. In a rat study, a loperamide-treated group (LOP) showed reduced water content in fecal pellets but showed an increased number of fecal pellets in the distal colon. In addition, the BE0623 yogurt (L-BE0623Y) group had the fewest fecal pellets in the distal colon. Regarding the serum lipid parameters, the LOP group had a high-density lipoprotein (HDL)/total cholesterol ratio that was 43% lower than that of a normal water group (NOR), but the outcome for the L-BE0623Y group was 27% lower than the NOR group. In a human study, 116 adults with IBS were sampled as subjects and fed 300 mL of yogurt per day for an eight week period. There was an IBS improvement in the L-BE0623Y and commercial yogurt (L-CY) groups, though flatulence, stool consistency and frequency of defecation outcomes were also noted. Specifically, the L-BE0623Y treatment group showed significant effects with regard to defecation duration and urgency after the consumption of the yogurt used in this study. These results suggest that the Bifidobacteria-enhanced yogurt has superior effects with regard to relieving loperamide-induced constipation in rats and that regular consumption of L-BE0623Y is effective to improve IBS in humans.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Conclusion
References
참고문헌 (30)
참고문헌 신청
Barbara G / 2004 / New pathophysiological mechanisms in irritable bowel syndrome / Alimentary Pharmacology and Therapeutics 20(suppl 2):1~9
Blanchard EB / 2008 / The role of stress in symptom exacerbation among IBS patients / Journal of Psychosomatic Research 64:119~128
Brandt LJ / 2009 / American college of gastroenterology task force on irritable bowel syndrome. An evidence-based position statement on the management of irritable bowel syndrome / The American Journal of Gastroenterology 104(suppl 1):S1~S35
Cann PA / 1984 / Role of loperamide and placebo in management of irritable bowel syndrome(IBS) / Digestive Diseases and Sciences 29:239~247
조영훈 / 2021 / Characteristics of fermented milk containing Bifidobacterium growth promoter (BE0623) and dietary fiber / Korean Journal of Agricultural Science 48(2):209~218
Blanchard EB / 2008 / The role of stress in symptom exacerbation among IBS patients / Journal of Psychosomatic Research 64:119~128
Brandt LJ / 2009 / American college of gastroenterology task force on irritable bowel syndrome. An evidence-based position statement on the management of irritable bowel syndrome / The American Journal of Gastroenterology 104(suppl 1):S1~S35
Cann PA / 1984 / Role of loperamide and placebo in management of irritable bowel syndrome(IBS) / Digestive Diseases and Sciences 29:239~247
조영훈 / 2021 / Characteristics of fermented milk containing Bifidobacterium growth promoter (BE0623) and dietary fiber / Korean Journal of Agricultural Science 48(2):209~218
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